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- Table of Contents
Facts about Pro-MCH.
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Human | |
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Gene Name: | PMCH |
Uniprot: | P20382 |
Entrez: | 5367 |
Belongs to: |
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melanin-concentrating hormone family |
MCHpro-MCH; pro-melanin-concentrating hormone
Mass (kDA):
18.679 kDA
Human | |
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Location: | 12q23.2 |
Sequence: | 12; NC_000012.12 (102196459..102199540, complement) |
Predominantly expressed in lateral hypothalamus, also detected in pallidum, neocortex and cerebellum. Also found in thymus, brown adipose tissue, duodenum and testis (spermatogonia, early spermatocytes and Sertoli cells). No expression in peripheral blood. In brain exclusively mature MCH and NEI peptides are present. In peripheral tissues a large product, encompassing the NEI and MCH domains of the precursor, is found predominantly.
Secreted.
PMID: 2149166 by Presse F., et al. Structure of the human melanin concentrating hormone mRNA.
PMID: 8326825 by Breton C., et al. Isolation and characterization of the human melanin-concentrating hormone gene and a variant gene.