Plexin-D1 Antibodies

AND PLXND1 ELISA kits, Plexin-D1 Proteins

Many biological assays use antibodies to detect Plexin-D1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Plexin-D1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Plexin-D1 antibodies...

We validate the specificity of these antibodies to Plexin-D1 by testing them on tissues known to express PLXND1 positively and negatively. Browse below to find the PLXND1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLXND1 Infographic by Boster Bio

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Anti-PLXD1 PLXND1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A05289
100ul

PLXND1 Overview

Facts about Plexin-D1.

PLXND1 3D structure. Source: alphafold

Plexin-D1 (PLXND1)

Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide array of cell types.

Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration.

Gene Information

Human
Gene Name:	PLXND1
Uniprot:	Q9Y4D7
Entrez:	23129

Family

Belongs to:

plexin family

Alternative Names

KIAA0620MGC75353; PLEXD1; Plexin D1; plexin-D1; PLXND1

Molecular Weight

Mass (kDA):
212.007 kDA

Genomic Context


Human

Location:	3q22.1
Sequence:	3; NC_000003.12 (129555214..129606676, complement)

Tissue Specificity

Detected at low levels in heart, placenta, lung, skeletal muscle, kidney, thymus and liver. Detected at very low levels in brain, colon, spleen, small intestine and peripheral blood leukocytes.

Subcellular Localizations

Cell membrane; Single-pass membrane protein. Cell projection, lamellipodium membrane.

Diseases

Tumor Angiogenesis
Neoplasms
Malignant Neoplasms
Neoplasm Metastasis
Pathologic Neovascularization
Nervousness
Melanoma
Tissue Adhesions
Neoplasm Invasiveness
Carcinoma
Tumor Progression
Mobius Syndrome

Cell Invasion
Brain Neoplasms
Stomach Neoplasms
Burkitt Lymphoma
Metastatic Malignant Neoplasm To The Liver
Malignant Tumor Of Colon

Interacting Proteins

NR4A1
SEMA3E
Sema3e
SEMA4A

Pathways

Angiogenesis
Cell Adhesion
Axon Guidance
Cell Migration
Cell Activation
Brain Development
Immune Response
Tube Formation
Neurogenesis
B Cell Activation
Vasculogenesis
Reflex
Cell Maturation

Cell Motility
Sprouting Angiogenesis
Cell Proliferation
Vasculature Development
Skeletal System Morphogenesis
Dna Methylation
Somitogenesis

PTMs

Methylation

Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLXND1

References

PMID: 12412018 by van der Zwaag B., et al. PLEXIN-D1, a novel plexin family member, is expressed in vascular endothelium and the central nervous system during mouse embryogenesis.

PMID: 20385769 by Sakurai A., et al. Semaphorin 3E initiates antiangiogenic signaling through plexin D1 by regulating Arf6 and R-Ras.