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- Table of Contents
Facts about Plexin-A4.
Coreceptor for SEMA3A.
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin.
Human | |
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Gene Name: | PLXNA4 |
Uniprot: | Q9HCM2 |
Entrez: | 91584 |
Belongs to: |
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plexin family |
A; DKFZp434G0625; FAYV2820; FLJ35026; FLJ38287; KIAA1550DKFZp566O0546; PLEXA4; Plexin A4; plexin A4, B; plexin-A4; PLXNA4; PLXNA4A; PLXNA4B; PRO34003
Mass (kDA):
212.455 kDA
Human | |
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Location: | 7q32.3 |
Sequence: | 7; NC_000007.14 (132123332..132648688, complement) |
Cell membrane; Single-pass type I membrane protein.
PMID: 14702039 by Ota T., et al. Complete sequencing and characterization of 21,243 full-length human cDNAs.
PMID: 12853948 by Hillier L.W., et al. The DNA sequence of human chromosome 7.