Phospholipid scramblase 4 Antibodies

AND PLSCR4 ELISA kits, Phospholipid scramblase 4 Proteins

Many biological assays use antibodies to detect Phospholipid scramblase 4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Phospholipid scramblase 4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Phospholipid scramblase 4 antibodies...

We validate the specificity of these antibodies to Phospholipid scramblase 4 by testing them on tissues known to express PLSCR4 positively and negatively. Browse below to find the PLSCR4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLSCR4 Infographic by Boster Bio

All PLSCR4 Products

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Product

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Specificity

Applications

Price

Anti-PLS4 PLSCR4 Antibody

Human

ELISA, WB

$380
Cat # A11039
100ul

PLSCR4 (NM_020353) Human Recombinant Protein

$813
Cat # PROTQ9NRQ2
20 µg

PLSCR4 Overview

Facts about Phospholipid scramblase 4.

PLSCR4 3D structure. Source: alphafold

Phospholipid scramblase 4 (PLSCR4)

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.

Gene Information

Human
Gene Name:	PLSCR4
Uniprot:	Q9NRQ2
Entrez:	57088

Family

Belongs to:

phospholipid scramblase family

Alternative Names

Ca(2+)-dependent phospholipid scramblase 4; cell growth inhibiting protein 43; Cell growth-inhibiting gene 43 protein; phospholipid scramblase 4; PL scramblase 4; TRA1

Molecular Weight

Mass (kDA):
37.005 kDA

Genomic Context


Human

Location:	3q24
Sequence:	3; NC_000003.12 (146192335..146251179, complement)

Tissue Specificity

Expressed in heart, brain, placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, uterus, small intestine and colon. Not detected in peripheral blood lymphocytes.

Subcellular Localizations

Membrane; Single-pass type II membrane protein.

Diseases

Inflammation
Dyslipidemias
Agranulocytosis
Postmortem Changes
Schizophrenia
Endometrial Polyp
Premature Birth
Cancer Patients And Suicide And Depression
Mental Disorders
Insulin Resistance

Obesity
Hiv Infections
Hyperlipidemia
Impaired Glucose Tolerance
Bipolar Disorder

Interacting Proteins

Hoxa1
MTUS2
NOTCH2NL
TRIP13

Pathways

Transport
Coagulation
Cellular Localization
Localization
Nuclear Transport
Nuclear Import

PTMs

Lipoprotein

Palmitate

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLSCR4

References

PMID: 10930526 by Wiedmer T., et al. Identification of three new members of the phospholipid scramblase gene family.

PMID: 18256029 by Shibata H., et al. Identification of Alix-type and non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.