PLK5 Antibodies

AND PLK5 ELISA kits, PLK5 Proteins

Many biological assays use antibodies to detect PLK5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLK5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLK5 antibodies...

We validate the specificity of these antibodies to PLK5 by testing them on tissues known to express PLK5 positively and negatively. Browse below to find the PLK5 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLK5 Infographic by Boster Bio

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PLK5 Overview

Facts about Inactive serine/threonine-protein kinase PLK5.

PLK5 3D structure. Source: alphafold

Inactive serine/threonine-protein kinase PLK5 (PLK5)

Inactive serine/threonine-protein kinase that plays a role in cell cycle development and neuronal differentiation. .

Gene Information

Human
Gene Name:	PLK5
Uniprot:	Q496M5
Entrez:	126520

Family

Belongs to:

protein kinase superfamily

Alternative Names

MGC118807; MGC118808; PLK5P; polo-like kinase 5; polo-like kinase 5, pseudogene; SgK384ps

Molecular Weight

Mass (kDA):
36.329 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (1524077..1536046)

Tissue Specificity

Expressed in the brain, neurons and glial cells. Also expressed in highly differentiated cells, such as the serous acini in the parotid gland, distal and proximal tubules of the kidney, tubules of the seminal gland, Kupffer cells and some hepatocytes in the liver, and some cells in the germinal center of lymph nodes (at protein level).

Subcellular Localizations

Nucleus, nucleolus. Cytoplasm.

Diseases

Neoplasms
Glioblastoma
Genotoxic Stress
Brain Neoplasms
Glioblastoma Multiforme
Malignant Neoplasms
Nervousness

Malignant Neoplasm Of Brain
Astrocytoma

Pathways

Cell Cycle
Regulation Of Kinase Activity
Cell Proliferation
Regulation Of Mitosis
Mitosis
Neuron Differentiation
Localization

Cell Cycle Arrest
Cytokinesis

PTMs

Methylation

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLK5

References

PMID: 21245385 by de Carcer G., et al. Plk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppression.