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Plet1 Antibodies
AND Plet1 ELISA kits, Plet1 Proteins
Many biological assays use antibodies to detect Plet1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Plet1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Plet1 antibodies...
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Plet1 Overview
Facts about Placenta-expressed transcript 1 protein.
Placenta-expressed transcript 1 protein (Plet1)
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins through a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.
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Gene Information
| Mouse | |
|---|---|
| Gene Name: | Plet1 |
| Uniprot: | Q8VEN2 |
| Entrez: | 76509 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
AgK114; C11orf34; chromosome 11 open reading frame 34; placenta expressed transcript 1; PLET1; PLET-1
Molecular Weight
Mass (kDA):
25.006 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 9|9 A5.3 |
| Sequence: | 9; |
Tissue Specificity
Present in hair follicle cells and sebaceous gland of skin, ciliated epithelial cells of trachea and bronchial tube, striated portion of submandibular gland, distal convoluted tubule cells of kidney, ciliated epithelial cells of oviduct, medulla of adrenal gland and anterior lobe of pituitary gland. Expressed in keratinocytes of the hair follicle at the trichilemmal zone corresponding to the terminally differentiated outermost suprabasal outer root sheath (ORS), including that of the sebaceous gland duct (SGD) and the directly adjacent upper distal end of the companion layer (CL). Expression is similar in all hair follicle growth stages. Also detected during both the early and late anagen phases above the bulge of stem cells. Expressed at the leading edge of the epidermal wound. Not expressed in the interfollicular epidermis (IFE), inner root sheath (IRS) and hair fiber. Highly expressed in placenta. Detected in mammary and prostate epithelia and in the pancreas (at protein level).
Diseases
- Endometrial Polyp
- Tissue Adhesions
Pathways
- Cell Adhesion
- Cellular Localization
- Immune Response
- Placenta Development
- Localization
PTMs
- Glycoprotein
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Plet1
bosterbio.com/bosterbio-gene-info-cards/Plet1
References
PMID: 15203209 by Zhao S.-H., et al. PLET1 (C11orf34), a highly expressed and processed novel gene in pig and mouse placenta, is transcribed but poorly spliced in human.
PMID: 16219980 by Takeuchi M., et al. Distribution of a novel protein AgK114 expression in the normal tissues of adult mice: dual expression of AgK114 and growth hormone in anterior pituitary cells.