PLA2G6 Antibodies

AND PLA2G6 ELISA kits, PLA2G6 Proteins

Many biological assays use antibodies to detect PLA2G6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLA2G6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLA2G6 antibodies...

We validate the specificity of these antibodies to PLA2G6 by testing them on tissues known to express PLA2G6 positively and negatively. Browse below to find the PLA2G6 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLA2G6 Infographic by Boster Bio

All PLA2G6 Products

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Product

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Specificity

Applications

Price

Anti-PLA2G6 Antibody Picoband®

7 Q&As

Human, Mouse, Rat

ELISA, WB

$370
Cat # A01648-1
100 μg/vial

Calcium independent Phospholipase A2 (PLA2G6) (NM_001004426) Human Recombinant Protein

$1249
Cat # PROTO60733
20 µg

Anti-Calcium independent Phospholipase A2 (PLA2G6) Mouse Monoclonal Antibody [Clone ID: OTI10G4]

Human, Mouse, Rat

$523
Cat # M01648
100 µl

Calcium independent Phospholipase A2 (PLA2G6) (NM_003560) Human Over-expression Lysate

Human

$628
Cat # LS008398
100 µg

PLA2G6 Overview

Facts about 85/88 kDa calcium-independent phospholipase A2.

PLA2G6 3D structure. Source: alphafold

85/88 kDa calcium-independent phospholipase A2 (PLA2G6)

Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production.

May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation.

Gene Information

Human
Gene Name:	PLA2G6
Uniprot:	O60733
Entrez:	8398

Family

Belongs to:

No superfamily

Alternative Names

calcium-independent phospholipase A2; EC 3.1.1.4; Group VI phospholipase A2; IPLA2; iPLA285 kDa calcium-independent phospholipase A2; IPLA2-VIA; NBIA2A; NBIA2B; PARK14GVI; patatin-like phospholipase domain containing 9; phospholipase A2, group VI (cytosolic, calcium-independent); PNPLA9

Molecular Weight

Mass (kDA):
89.903 kDA

Genomic Context


Human

Location:	22q13.1
Sequence:	22; NC_000022.11 (38111495..38181830, complement)

Tissue Specificity

Four different transcripts were found to be expressed in a distinct tissue distribution.

Subcellular Localizations

[Isoform LH-iPLA2]: Membrane; Peripheral membrane protein. Recruited to the membrane-enriched pseudopod upon MCP1/CCL2 stimulation in monocytes.; [Isoform SH-iPLA2]: Cytoplasm.

Diseases

Neuroaxonal Dystrophies
Nerve Degeneration
Dystrophy
Infantile Neuroaxonal Dystrophy
Neurodegenerative Disorders
Inflammation
Parkinson Disease
Atrophy
Secondary Parkinson Disease
Dystonia Disorders
Malignant Neoplasms
Hallervorden-spatz Syndrome

Cancer Patients And Suicide And Depression
Nervousness
Neoplasms
Globus Hystericus
Insulinoma
Movement Disorders
Iron Metabolism Disorders

Pathways

Cell Death
Pathogenesis
Localization
Cell Cycle
Secretion
Cell Proliferation
Insulin Secretion
Cell Growth
Translation
Inflammatory Response
Chemotaxis
Phagocytosis
Apoptotic Process

Cell Migration
Coagulation
S Phase
Transport
Monocyte Chemotaxis
Cell Cycle Arrest
Phospholipid Homeostasis

PTMs

Phosphorylation
Cleavage

Oxidation
Methylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLA2G6

References

PMID: 9417066 by Larsson P.K.A., et al. Multiple splice variants of the human calcium-independent phospholipase A2 and their effect on enzyme activity.

PMID: 10336645 by Larsson Forsell P.K.A., et al. The human calcium-independent phospholipase A2 gene. Multiple enzymes with distinct properties from a single gene.