PLA2G3 Antibodies

AND PLA2G3 ELISA kits, PLA2G3 Proteins

Many biological assays use antibodies to detect PLA2G3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLA2G3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLA2G3 antibodies...

We validate the specificity of these antibodies to PLA2G3 by testing them on tissues known to express PLA2G3 positively and negatively. Browse below to find the PLA2G3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLA2G3 Infographic by Boster Bio

All PLA2G3 Products

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Specificity

Applications

Price

Anti-PLA2G3 Mouse Monoclonal Antibody [Clone ID: OTI1F4]

Human

$523
Cat # M07886
100 µl

Anti-PLA2G3 Antibody Picoband®

Human, Mouse

ELISA, Flow Cytometry, WB

$370
Cat # A07886-1
100 µg/vial

PLA2G3 Overview

Facts about Group 3 secretory phospholipase A2.

PLA2G3 3D structure. Source: alphafold

Group 3 secretory phospholipase A2 (PLA2G3)

PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Shows an 11-fold taste for phosphatidylglycerol over phosphatidylcholine (PC).

Preferential cleavage: 1-palmitoyl-2-linoleoyl- phosphatidylethanolamine (PE) > 1-palmitoyl-2-linoleoyl-PC > 1- palmitoyl-2-arachidonoyl-PC > 1-palmitoyl-2-arachidonoyl-PE. Plays a role in ciliogenesis.

Gene Information

Human
Gene Name:	PLA2G3
Uniprot:	Q9NZ20
Entrez:	50487

Family

Belongs to:

phospholipase A2 family

Alternative Names

EC 3.1.1.4; GIII sPLA2; GIII-SPLA2; group 3 secretory phospholipase A2; group III secreted phospholipase A2; Group III secretory phospholipase A2; Phosphatidylcholine 2-acylhydrolase 3; phosphatidylcholine 2-acylhydrolase GIII; phospholipase A2, group III; SPLA2III; sPLA2-III

Molecular Weight

Mass (kDA):
57.167 kDA

Genomic Context


Human

Location:	22q12.2
Sequence:	22; NC_000022.11 (31134807..31140508, complement)

Tissue Specificity

Expressed in kidney, heart, liver, and skeletal muscle. Also present in placenta and peripheral blood leukocytes. Not detected in brain, colon, thymus, spleen and small intestine. In lung, expressed in bronchial epithelial cells and alveolar macrophages, but scarcely detected in alveolar epithelium, arterial walls and interstitial fibroblasts (at protein level). In joints of osteoarthritis and rheumatoid arthritis, expressed in endothelial cells (at protein level). In normal heart, detected in some vessels. In myocardial tissues with acute infarction, expressed in vascular endothelial cells adjacent to cardiomyocytes and those in lesions with granulation. Expression in cardiomyocytes is scarce (at protein level). In uterus, breast and colon cancers, detected in tumor cells and neighboring microvascular endothelium, but not in normal glandular tissues (at protein level).