Pip5k1c Antibodies

AND Pip5k1c ELISA kits, Pip5k1c Proteins

Many biological assays use antibodies to detect Pip5k1c, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pip5k1c in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pip5k1c antibodies...

We validate the specificity of these antibodies to Pip5k1c by testing them on tissues known to express Pip5k1c positively and negatively. Browse below to find the Pip5k1c antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Pip5k1c Infographic by Boster Bio

All Pip5k1c Products

Product

Figures

Specificity

Applications

Price

Anti-PIPK I gamma PIP5K1C Antibody

7 Q&As

Human

$399
Cat # A05687
100μl

Anti-PIP5KI Gamma PIP5K1C Antibody

Human, Mouse, Rat

$405
Cat # A05687-1
100ul

Pip5k1c Overview

Facts about Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma.

Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (Pip5k1c)

PtdIns(4,5)P2 is involved in many different cellular processes and is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. Nearly all PtdIns(4,5)P2 is considered to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P.

Participates in many different cellular processes like vesicle mediated transport, cell adhesion, cell polarization and cell migration. Together with PIP5K1A is required for phagocytosis, but they govern different types of actin remodeling in sequential steps.

Gene Information

Mouse
Gene Name:	Pip5k1c
Uniprot:	O70161
Entrez:	18717

Family

Belongs to:

No superfamily

Alternative Names

EC 2.7.1; EC 2.7.1.68; KIAA0589diphosphoinositide kinase; LCCS3Human homolog of mouse phosphatidylinositol-4-phosphate 5-kinase I-gamma; Phosphatidylinositol-4-phosphate 5-kinase type I gamma; phosphatidylinositol-4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma; PIP5K1-gamma; PIP5Kgamma; PIP5K-GAMMA; PIP5KIgamma; PIPKIg_v4; PtdIns(4)P-5-kinase 1 gamma; type I PIP kinase

Molecular Weight

Mass (kDA):
72.408 kDA

Genomic Context


Mouse

Location:	10\|10 C1
Sequence:	10;

Tissue Specificity

High expression in brain. Also detected in lung, thymus, heart, testicle, kidney and embryo. Highly expressed in forebrain, in particular in cerebellum, hippocampus and cerebral cortex.

Diseases

Neurogenic Urinary Bladder
Blepharoptosis
Arthrogryposis
Inflammation
Nervous System Disorder
Pelvic Organ Prolapse

Tissue Adhesions

Pathways

Transport
Actin Cytoskeleton Reorganization
Vesicle Transport
Chemotaxis
Neutrophil Chemotaxis
Fibroblast Proliferation
Integrin Activation

Endocytosis
Spermatogenesis

PTMs

Phosphorylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Pip5k1c

References

PMID: 9535851 by Ishihara H., et al. Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family.

PMID: 12422220 by Ling K., et al. Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions.