PIK3R5 Antibodies

AND PIK3R5 ELISA kits, PIK3R5 Proteins

Many biological assays use antibodies to detect PIK3R5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PIK3R5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PIK3R5 antibodies...

We validate the specificity of these antibodies to PIK3R5 by testing them on tissues known to express PIK3R5 positively and negatively. Browse below to find the PIK3R5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PIK3R5 Infographic by Boster Bio

All PIK3R5 Products

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Product

Figures

Specificity

Applications

Price

Anti-PIK3R5/Pi 3 Kinase P101 Antibody

4 Q&As

Human, Mouse

IF, IHC, WB

$360
Cat # A02827
100 µl

Anti-PI 3-kinase p101 PIK3R5 Antibody

Human, Mouse

ELISA, IHC, WB

$380
Cat # A02827-1
100ul

Anti-PIK3R5 Mouse Monoclonal Antibody [Clone ID: OTI4G9]

Dog, Human, Monkey, Mouse, Rat

IF, IHC, WB

$523
Cat # M02827
100 µl

Anti-PIK3R5 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A02827-2
100 µg/vial

PIK3R5 Overview

Facts about Phosphoinositide 3-kinase regulatory subunit 5.

PIK3R5 3D structure. Source: alphafold

Phosphoinositide 3-kinase regulatory subunit 5 (PIK3R5)

Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers.

Required for G protein-mediated activation of PIK3CG (By similarity). .

Gene Information

Human
Gene Name:	PIK3R5
Uniprot:	Q8WYR1
Entrez:	23533

Family

Belongs to:

No superfamily

Alternative Names

F730038I15Rik; FOAP-2; p101; p101-PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit; phosphoinositide-3-kinase, regulatory subunit 5; phosphoinositide-3-kinase, regulatory subunit, polypeptide p101; PI3-kinase p101 subunit; PI3-kinase regulatory subunit 5; PIK3R5; PtdIns-3-kinase regulatory subunit; regulatory subunit 5, p101

Molecular Weight

Mass (kDA):
97.348 kDA

Genomic Context


Human

Location:	17p13.1
Sequence:	17; NC_000017.11 (8878916..8965712, complement)

Tissue Specificity

Ubiquitously expressed with high expression in fetal brain compared to adult brain. Abundant expression is observed in cerebellum, cerebral cortex, cerebral meninges, and vermis cerebelli.

Subcellular Localizations

Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein. Predominantly localized in the nucleus in absence of PIK3CG/p120. Colocalizes with PIK3CG/p120 in the cytoplasm. Translocated to the plasma membrane in a beta-gamma G protein-dependent manner.

Diseases

Apraxias
Metastatic Melanoma
Melanoma
Ataxia
Neurofibromatosis 1
Atrophy
Premature Aging Syndrome
Ataxia Telangiectasia

Malignant Neoplasms
Oculomotor Apraxia
Neoplasms

Pathways

Drug Resistance
Aging

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PIK3R5

References

PMID: 15797027 by Suire S., et al. p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma.

PMID: 22065524 by Tassan N.A., et al. A missense mutation in PIK3R5 gene in a family with ataxia and oculomotor apraxia.