PIK3R3 Antibodies

AND PIK3R3 ELISA kits, PIK3R3 Proteins

Many biological assays use antibodies to detect PIK3R3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PIK3R3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PIK3R3 antibodies...

We validate the specificity of these antibodies to PIK3R3 by testing them on tissues known to express PIK3R3 positively and negatively. Browse below to find the PIK3R3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PIK3R3 Infographic by Boster Bio

All PIK3R3 Products

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Product

Figures

Specificity

Applications

Price

Anti-PI 3 Kinase p55 gamma PIK3R3 Rabbit Monoclonal Antibody

3 Q&As

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M06707
100 μl

Anti-P55G PIK3R3 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A06707
100ul

Anti-PIK3R3 Antibody (C-term)

Human

IF, IHC-P, WB

$299
Cat # A06707-1
80 µl

PI 3 Kinase p55 gamma (PIK3R3) (NM_003629) Human Over-expression Lysate

Human

$628
Cat # LS008503
100 µg

PIK3R3 Overview

Facts about Phosphatidylinositol 3-kinase regulatory subunit gamma.

PIK3R3 3D structure. Source: alphafold

Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3)

Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.

Gene Information

Human
Gene Name:	PIK3R3
Uniprot:	Q92569
Entrez:	8503

Family

Belongs to:

PI3K p85 subunit family

Alternative Names

100% homology to SWISS-PROT Q92569; DKFZp686P05226; FLJ41892; p55; p55PIK; Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; phosphoinositide-3-kinase, regulatory subunit 3 (gamma); phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma); phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma); PI 3Kinase p55 gamma; PI 3-Kinase p55 gamma; PI3K regulatory subunit gamma; PI3-kinase subunit p55-gamma; PIK3R3; regulatory subunit, polypeptide 3 (p55, gamma)

Molecular Weight

Mass (kDA):
54.448 kDA

Genomic Context


Human

Location:	1p34.1
Sequence:	1; NC_000001.11 (46040140..46174901, complement)

Tissue Specificity

Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Malignant Neoplasm Of Ovary
Glioblastoma
Tissue Adhesions
Retinoblastoma
Brain Ischemia
Non-neoplastic Disorder
Malignant Tumor Of Colon
Glioma
Malignant Neoplasm Of Urinary Bladder

Tumor Angiogenesis
Epithelial Ovarian Cancer
Ovarian Neoplasm
Bacterial Infections
Ischemia
Chronic Infectious Disease
Pneumonia, Ventilator-associated

Interacting Proteins

ABI1
AR
CBL
CEP19
CRK

CRYBA2
EGFR
ERBB2
ERBB3
FRS3

GAB1
HTT
IGF1R
IRS1
KIT

MET
METTL27
OLIG1
OTUD7B
PELI3

PIK3CA
PIK3CB
PIK3CD
PLEKHS1
PTK2

RBP7
SH2D2A
SOCS4
SPSB2
SRC

TSPAN2
WDFY3

Pathways

Cell Cycle
Cell Cycle Arrest
Cell Proliferation
Vascular Smooth Muscle Contraction
Cell Migration
Smooth Muscle Contraction
Mitosis
Dna Methylation
Muscle Contraction
Methylation
Reverse Transcription

Translation
Phagocytosis
Cell Motility
Angiogenesis
Pathogenesis
Secretion

PTMs

Phosphorylation

Cleavage

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PIK3R3

References

PMID: 9524259 by Dey B.R., et al. Cloning of human p55 gamma, a regulatory subunit of phosphatidylinositol 3-kinase, by a yeast two-hybrid library screen with the insulin-like growth factor-I receptor.

PMID: 12470648 by Hafizi S., et al. Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensin.