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- Table of Contents
Facts about GPI mannosyltransferase 4.
The presence of a fourth mannose in GPI is facultative and just scarcely detected, suggesting that it only exists in some cells. .
Human | |
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Gene Name: | PIGZ |
Uniprot: | Q86VD9 |
Entrez: | 80235 |
Belongs to: |
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glycosyltransferase 22 family |
class Z; EC 2.4.1; EC 2.4.1.-; FLJ12768; GPI mannosyltransferase 4; GPI mannosyltransferase IV; GPI-MT-IV; hSMP3; phosphatidylinositol glycan anchor biosynthesis, class Z; Phosphatidylinositol-glycan biosynthesis class Z protein; PIG-Z; SMP3 mannosyltransferase; SMP3SMP3 homolog
Mass (kDA):
63.471 kDA
Human | |
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Location: | 3q29 |
Sequence: | 3; NC_000003.12 (196946356..196969411, complement) |
Widely expressed at low level, with highest level in brain and colon.
Endoplasmic reticulum membrane; Multi-pass membrane protein.
PMID: 15208306 by Taron B.W., et al. Human Smp3p adds a fourth mannose to yeast and human glycosylphosphatidylinositol precursors in vivo.