This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
, No Gclids
PIBF1 Antibodies
AND PIBF1 ELISA kits, PIBF1 Proteins
Many biological assays use antibodies to detect PIBF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PIBF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PIBF1 antibodies...
Previous: CCN4
Next: PPIH
PIBF1 Infographic by Boster Bio
All PIBF1 Products
Product
Figures
Specificity
Applications
Price
PIBF1 Overview
Facts about Progesterone-induced-blocking factor 1.
Progesterone-induced-blocking factor 1 (PIBF1)
Plays a role in ciliogenesis. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PIBF1 |
| Uniprot: | Q8WXW3 |
| Entrez: | 10464 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
C13orf24; chromosome 13 open reading frame 24; KIAA1008; PIBF; PIBF1; progesterone immunomodulatory binding factor 1; progesterone-induced blocking factor 1; progesterone-induced-blocking factor 1; RP11-505F3.1
Molecular Weight
Mass (kDA):
89.805 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 13q21.33-q22.1 |
| Sequence: | 13; NC_000013.11 (72782133..73016461) |
Tissue Specificity
Expressed at highest levels in testis. Moderate expression is detected in spleen, thymus, prostate, ovary, small intestine, and colon (PubMed:11935316). Expressed in the first trimester pregnancy decidua (PubMed:12516630). Localized to extravillous cytotrophoblast (at protein level). Also found in syncytiotrophoblast and part of the villous cytotrophoblast. Isoform 1 is expressed in first trimester and term villous trophoblast; trophoblast cells can additionally express other isoforms (PubMed:18817979). Overexpressed in solid tumors from stomach and uterus and in cells from ovary, cervical, breast, lymphoma and leukemia cancer (PubMed:25218441).
Subcellular Localizations
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Secreted. In progesterone-treated astrocytoma cells a 57 kDa protein and isoform 1 (90 kDa) have been described, both being located in the intracellular medium and secreted. Respective predominant forms are isoform 1 in the intracellular and the 57 kDa protein in the extracellular medium (PubMed:25218441).; [Isoform 1]: Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Secreted. Localizes to centriola
Diseases
- Neoplasms
- Malignant Neoplasms
- Cell Invasion
- Premature Obstetric Labor
- Endometrial Polyp
- Malignant Paraganglionic Neoplasm
- Leukemia
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Cell Transformation, Neoplastic
Interacting Proteins
- CEP63
- HTT
- PCM1
Pathways
- Cytokine Production
- Immune Response
- Secretion
- Fertilization
- Ovulation
- Progesterone Secretion
- Glycosylation
- Cytokine Secretion
- Oxidative Phosphorylation
- Localization
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PIBF1
bosterbio.com/bosterbio-gene-info-cards/PIBF1
References
PMID: 11935316 by Rozenblum E., et al. A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes.
PMID: 15305375 by Lachmann M., et al. PIBF (progesterone induced blocking factor) is overexpressed in highly proliferating cells and associated with the centrosome.