Elafin Antibodies

AND PI3 ELISA kits, Elafin Proteins

Many biological assays use antibodies to detect Elafin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Elafin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Elafin antibodies...

We validate the specificity of these antibodies to Elafin by testing them on tissues known to express PI3 positively and negatively. Browse below to find the PI3 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PI3 Infographic by Boster Bio

All PI3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Elafin/Skalp/PI3 Antibody Picoband®

3 Q&As

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # PB9957
100 μg/vial

Human Elafin/PI3 ELISA Kit PicoKine®

10 Q&As

Human

ELISA

$499
Cat # EK1117
96 wells/kit, with removable strips.

Human Elafin/PI3 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Human

ELISA

$500
Cat # EZ1117
For 5 plates, 96 wells each

Anti-Elafin/Skalp PI3 Antibody (monoclonal, C7)

Human

ELISA, IHC

$370
Cat # M00364
100 μg/vial

PI3 (NM_002638) Human Recombinant Protein

$813
Cat # PROTP19957
20 µg

Human Elafin/PI3 PicoKine® Quick ELISA Kit

Human

ELISA

$499
Cat # FEK1117
96 wells/kit, with removable strips.

PI3 (NM_002638) Human Over-expression Lysate

Human

$628
Cat # LS005266
100 µg

PI3 Overview

Facts about Elafin.

PI3 3D structure. Source: alphafold

Elafin (PI3)

Neutrophil and pancreatic elastase-specific inhibitor of skin. It might prevent elastase-mediated tissue proteolysis.

Gene Information

Human
Gene Name:	PI3
Uniprot:	P19957
Entrez:	5266

Family

Belongs to:

No superfamily

Alternative Names

cementoin; Elafin; Elastase-specific inhibitor; ESI; ESIWAP four-disulfide core domain protein 14; Peptidase inhibitor 3; peptidase inhibitor 3, skin-derived; PI3; PI-3; pre-elafin; protease inhibitor 3, skin-derived (SKALP); Protease inhibitor WAP3; SKALP; SKALPELAFIN; Skin-derived antileukoproteinase; Trappin2; Trappin-2; WAP four-disulfide core domain 14; WAP3MGC13613; WFDC14elafin

Molecular Weight

Mass (kDA):
12.27 kDA

Genomic Context


Human

Location:	20q13.12
Sequence:	20; NC_000020.11 (45174902..45176544)

Subcellular Localizations

Secreted.

Diseases

Malignant Neoplasms
Neoplasms
Inflammation
Carcinoma
Tissue Adhesions
Tumor Angiogenesis
Cell Transformation, Neoplastic
Mammary Neoplasms
Malignant Neoplasm Of Breast
Diabetes Mellitus
Malignant Paraganglionic Neoplasm
Cell Invasion

Ischemia
Leukemia
Neoplasm Metastasis
Hypoxia
Insulin Resistance
Nervousness
Virus Diseases

Pathways

Cell Proliferation
Cell Death
Secretion
Cell Cycle
Cell Growth
Angiogenesis
Pathogenesis
Cell Migration
Localization
Transport
Immune Response
Translation
Autophagy

Cell Cycle Arrest
Chemotaxis
Neuroprotection
Inflammatory Response
Cell Activation
Cell Adhesion
Rna Interference

PTMs

Phosphorylation
Cleavage
Dephosphorylation
Ubiquitination
Oxidation
Reduction
Methylation
Myristoylation
Prenylation
Ribosylation

Deacetylation
Glycosylation
Biotinylation
Carboxylation
Farnesylation
Acetylation
Palmitoylation
Sumoylation
Nitration
Geranylgeranylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PI3

References

PMID: 1339270 by Saheki T., et al. Primary structure of the human elafin precursor preproelafin deduced from the nucleotide sequence of its gene and the presence of unique repetitive sequences in the prosegment.

PMID: 7685029 by Molhuizen H.O.F., et al. SKALP/elafin: an elastase inhibitor from cultured human keratinocytes. Purification, cDNA sequence, and evidence for transglutaminase cross-linking.