GPI inositol-deacylase Antibodies

AND PGAP1 ELISA kits, GPI inositol-deacylase Proteins

Many biological assays use antibodies to detect GPI inositol-deacylase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPI inositol-deacylase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPI inositol-deacylase antibodies...

We validate the specificity of these antibodies to GPI inositol-deacylase by testing them on tissues known to express PGAP1 positively and negatively. Browse below to find the PGAP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PGAP1 Infographic by Boster Bio

All PGAP1 Products

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Product

Figures

Specificity

Applications

Price

Anti-PGAP1 Antibody (N-Term)

Human, Mouse, Rat

Flow Cytometry, IF, WB

$299
Cat # M08640
50 µl

Anti-PGAP1 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A08640
100 µg/vial

PGAP1 Overview

Facts about GPI inositol-deacylase.

PGAP1 3D structure. Source: alphafold

GPI inositol-deacylase (PGAP1)

Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transportation of GPI-anchored proteins in the endoplasmic reticulum to the Golgi (By similarity).

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Gene Information

Human
Gene Name:	PGAP1
Uniprot:	Q75T13
Entrez:	80055

Family

Belongs to:

GPI inositol-deacylase family

Alternative Names

Bst1; EC 3.1; FLJ12377; FLJ42774; GPI deacylase; GPI inositol-deacylase; hPGAP1; ISPD3024; post-GPI attachment to proteins 1; Post-GPI attachment to proteins factor 1

Molecular Weight

Mass (kDA):
105.383 kDA

Genomic Context


Human

Location:	2q33.1
Sequence:	2; NC_000002.12 (196833004..196926995, complement)

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Otocephaly
Congenital Abnormality
Holoprosencephaly
Microphthalmos
Microstomia
Jaw Abnormalities
Overlying Behavior
Male Infertility
Melanoma
Anophthalmos
Sterility

Infertility
Microglossia
Dysgnathia Complex
Growth Retardation
Uniparental Disomy

Pathways

Transport
Fertilization
Endoderm Formation
Secretory Pathway
Regulation Of Intracellular Protein Transport
Brain Development
Transcytosis
Protein Transport
Localization

Conjugation
Intracellular Protein Transport
Forebrain Development
Secretion

PTMs

Gpi Anchoring

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PGAP1

References

PMID: 14734546 by Tanaka S., et al. Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p.

PMID: 24784135 by Murakami Y., et al. Null mutation in PGAP1 impairing Gpi-anchor maturation in patients with intellectual disability and encephalopathy.