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Prefoldin subunit 5 Antibodies

AND PFDN5 ELISA kits, Prefoldin subunit 5 Proteins

Many biological assays use antibodies to detect Prefoldin subunit 5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prefoldin subunit 5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prefoldin subunit 5 antibodies...

We validate the specificity of these antibodies to Prefoldin subunit 5 by testing them on tissues known to express PFDN5 positively and negatively. Browse below to find the PFDN5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PFDN5 Infographic by Boster Bio

PFDN5 protein infographic

All PFDN5 Products

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Product

Figures

Specificity

Applications

Price

Anti-Prefoldin subunit 5 PFDN5 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A09908
100ul

Human PFDN5 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ99471
Starting from 20ug

Anti-PFDN5 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, IHC, WB

$370
Cat # M09908
100 μl/vial

PFDN5 (NM_002624) Human Over-expression Lysate

Human

$628
Cat # LS005204
100 µg

PFDN5 Overview

Facts about Prefoldin subunit 5.

PFDN5 3D structure

PFDN5 3D structure. Source: alphafold

Prefoldin subunit 5 (PFDN5)

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

Represses the transcriptional activity of MYC. .

Gene Information

Human
Gene Name:	PFDN5
Uniprot:	Q99471
Entrez:	5204

Gene Information

Family

Belongs to:

prefoldin subunit alpha family

Family

Alternative Names

c-myc binding protein; C-Myc-binding protein Mm-1; MM-1; MM1MGC71907; Myc modulator 1; myc modulator-1; PFD5MGC5329; prefoldin 5; prefoldin subunit 5

Molecular Weight

Mass (kDA):
17.328 kDA

Molecular Weight

Genomic Context


Human

Location:	12q13.13
Sequence:	12; NC_000012.12 (53295451..53299450)

Tissue Specificity

Highly expressed in pancreas and skeletal muscle and moderately in other tissues.

Subcellular Localizations

[Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Nucleus.

Subcellular Localization

Diseases

Neoplasms
Lymphoma
Leukemia
Malignant Neoplasms
Cytogenetic Abnormality
Cell Transformation, Neoplastic
Autoimmunity
Adenoma
Tongue Neoplasms
Malignant Neoplasm Of Tongue
Neoplasms, Experimental
Infertility

Carcinoma
Carcinogenesis
Tongue Squamous Cell Carcinoma
Nervousness
Asthma
Chronic Kidney Disease
Lupus Erythematosus, Systemic

Disease

Interacting Proteins

CALCOCO2
GLRX3
IKZF3
LINC01600
PFDN2

PSME3
VBP1

Interacting Proteins

Pathways

Cell Proliferation
Cell Cycle
Protein Folding
Cell Adhesion
Cellular Process
Hypersensitivity
Establishment Of Protein Localization
Localization
Cell Death
Regulation Of Cell Proliferation

Cell Growth
Mating
Pathogenesis
Secretion
Chromatin Remodeling

Pathways

PTMs

Ubiquitination

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PFDN5

References

PMID: 9792694 by Mori K., et al. MM-1, a novel c-Myc-associating protein that represses transcriptional activity of c-Myc.

PMID: 11567024 by Fujioka Y., et al. MM-1, a c-Myc-binding protein, is a candidate for a tumor suppressor in leukemia/lymphoma and tongue cancer.