PDP2 Antibodies

AND PDP2 ELISA kits, PDP2 Proteins

Many biological assays use antibodies to detect PDP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDP2 antibodies...

We validate the specificity of these antibodies to PDP2 by testing them on tissues known to express PDP2 positively and negatively. Browse below to find the PDP2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDP2 Infographic by Boster Bio

All PDP2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PDP2 Antibody

3 Q&As

Human

$399
Cat # A12472
100μl

PDP2 (NM_020786) Human Recombinant Protein

$813
Cat # PROTQ9P2J9
20 µg

PDP2 (NM_020786) Human Over-expression Lysate

Human

$628
Cat # LS057546
100 µg

PDP2 Overview

Facts about [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial.

PDP2 3D structure. Source: alphafold

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial (PDP2)

Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. .

Gene Information

Human
Gene Name:	PDP2
Uniprot:	Q9P2J9
Entrez:	57546

Family

Belongs to:

PP2C family

Alternative Names

EC 3.1.3; EC 3.1.3.43; KIAA1348[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial; PDP 2; PDPC 2; PPM2C2; protein phosphatase 2C, magnesium-dependent, catalytic subunit 2; Pyruvate dehydrogenase phosphatase catalytic subunit 2; pyruvate dehydrogenase phosphatase isoenzyme 2; pyruvate dehydrogenase phosphatase, catalytic subunit 2; pyruvate dehyrogenase phosphatase catalytic subunit 2

Molecular Weight

Mass (kDA):
59.978 kDA

Genomic Context


Human

Location:	16q22.1
Sequence:	16; NC_000016.10 (66880515..66891101)

Subcellular Localizations

Mitochondrion matrix.

Diseases

Lactic Acidemia With Pyruvate Dehydrogenase Phosphatase Deficiency
Diabetes Mellitus
Diabetes Mellitus, Experimental
Obesity
Dyslipidemias
Malnutrition
Diabetic Nephropathy
Inborn Errors Of Metabolism
Irido-corneal Dysgenesis
Hypoxia
Eye Abnormalities
Insulin Resistance

Chronic Mountain Sickness
Hyperlipidemia
Hyperglycemia
Dog Diseases
Anoxia
Lactic Acidemia
Altitude Sickness

Pathways

Glycolysis
Hyperphosphorylation
Pyruvate Oxidation
Gluconeogenesis
Fatty Acid Oxidation

PTMs

Phosphorylation

Oxidation

Dephosphorylation

Research Areas

Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDP2

References

PMID: 10718198 by Nagase T., et al. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

PMID: 14702039 by Ota T., et al. Complete sequencing and characterization of 21,243 full-length human cDNAs.