PDP1 Antibodies

AND PDP1 ELISA kits, PDP1 Proteins

Many biological assays use antibodies to detect PDP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDP1 antibodies...

We validate the specificity of these antibodies to PDP1 by testing them on tissues known to express PDP1 positively and negatively. Browse below to find the PDP1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDP1 Infographic by Boster Bio

All PDP1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PDP1 Antibody

Human, Mouse

$405
Cat # A05607
100ul

Anti-PPM2C PDP1 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A05607-1
100ul

PDP1 (NM_018444) Human Recombinant Protein

$813
Cat # PROTQ9P0J1
20 µg

Anti-PDP1/PDP Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A05607-2
100 μg/vial

PDP1 Overview

Facts about [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial.

PDP1 3D structure. Source: alphafold

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP1)

Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. .

Gene Information

Human
Gene Name:	PDP1
Uniprot:	Q9P0J1
Entrez:	54704

Family

Belongs to:

PP2C family

Alternative Names

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; EC 3.1.3; EC 3.1.3.43; MGC119646; PDH; PDP 1; PDP1; PDPC 1; PDPC; PDPFLJ32517; PPM2C; PPM2CFLJ56179; Protein phosphatase 2C; protein phosphatase 2C, magnesium-dependent, catalytic subunit; pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase; Pyruvate dehydrogenase phosphatase catalytic subunit 1; Pyruvate Dehydrogenase Phosphatase; pyruvate dehyrogenase phosphatase catalytic subunit 1

Molecular Weight

Mass (kDA):
61.054 kDA

Genomic Context


Human

Location:	8q22.1
Sequence:	8; NC_000008.11 (93916923..93926068)

Subcellular Localizations

Mitochondrion matrix.

Diseases

Lactic Acidemia With Pyruvate Dehydrogenase Phosphatase Deficiency
Diabetes Mellitus
Malnutrition
Brain Injuries
Acidosis
Traumatic Brain Injury
Obesity
Inborn Errors Of Metabolism
Insulin Resistance
Nervousness
Pyruvate Dehydrogenase Complex Deficiency Disease
Hyperglycemia
Neonatal Hypotonia

Dog Diseases
Hypoglycemia
Lactic Acidemia
Enzymopathy
Endoreduplication
Developmental Delay (disorder)
Acidemia

Interacting Proteins

CBFA2T2

Pathways

Circadian Behavior
Localization
Glycolysis
Pyruvate Oxidation
Tricarboxylic Acid Cycle
Methylation
Transport
Hyperphosphorylation
Cell Activation
Muscle Contraction
Gluconeogenesis
Reflex
Glucose Homeostasis

Proboscis Extension Reflex
Mitochondrial Translocation
Histone Acetylation
Feeding Behavior
Histone Methylation
Circadian Rhythm
Mitosis

PTMs

Phosphorylation
Dephosphorylation
Oxidation

Acetylation
Methylation
Decarboxylation

Prenylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDP1

References

PMID: 15855260 by Maj M.C., et al. Pyruvate dehydrogenase phosphatase deficiency: identification of the first mutation in two brothers and restoration of activity by protein complementation.