PDIA6 Antibodies

AND PDIA6 ELISA kits, PDIA6 Proteins

Many biological assays use antibodies to detect PDIA6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDIA6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDIA6 antibodies...

We validate the specificity of these antibodies to PDIA6 by testing them on tissues known to express PDIA6 positively and negatively. Browse below to find the PDIA6 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDIA6 Infographic by Boster Bio

All PDIA6 Products

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Product

Figures

Specificity

Applications

Price

Anti-PDIA6/Erp5 Rabbit Monoclonal Antibody

6 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # M03813
100 μl

Anti-Protein disulfide-isomerase A6 PDIA6 Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A03813
100ul

Anti-Protein disulfide-isomerase A6 PDIA6 Antibody

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$405
Cat # A03813-1
100ul

Anti-PDIA6 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03813-2
100 μg/vial

Human PDIA6 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ15084
Starting from 20ug

Anti-PDIA6 Antibody Picoband® (monoclonal, 3H5E7)

Human, Monkey

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03813-1
100 μg/vial

PDIA6 (NM_005742) Human Over-expression Lysate

Human

$628
Cat # LS010130
100 µg

PDIA6 Overview

Facts about Protein disulfide-isomerase A6.

PDIA6 3D structure. Source: alphafold

Protein disulfide-isomerase A6 (PDIA6)

May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390).

May also regulate the UPR through the EIF2AK3 UPR detector (PubMed:24508390). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936).

Gene Information

Human
Gene Name:	PDIA6
Uniprot:	Q15084
Entrez:	10130

Family

Belongs to:

protein disulfide isomerase family

Alternative Names

EC 5.3.4.1; Endoplasmic reticulum protein 5; ERp5; ERP5ER protein 5; P5TXNDC7; protein disulfide isomerase family A, member 6; Protein disulfide isomerase P5; protein disulfide isomerase-associated 6; protein disulfide isomerase-related protein; protein disulfide-isomerase A6; thioredoxin domain containing 7 (protein disulfide isomerase); Thioredoxin domain-containing protein 7

Molecular Weight

Mass (kDA):
48.121 kDA

Genomic Context


Human

Location:	2p25.1
Sequence:	2; NC_000002.12 (10783391..10837712, complement)

Tissue Specificity

Expressed in platelets (at protein level).

Subcellular Localizations

Endoplasmic reticulum lumen. Cell membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545).