PDE8A Antibodies

AND PDE8A ELISA kits, PDE8A Proteins

Many biological assays use antibodies to detect PDE8A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDE8A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDE8A antibodies...

We validate the specificity of these antibodies to PDE8A by testing them on tissues known to express PDE8A positively and negatively. Browse below to find the PDE8A antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDE8A Infographic by Boster Bio

All PDE8A Products

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Product

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Specificity

Applications

Price

Anti-PDE8A Purified Monoclonal Antibody

Human

$330
Cat # M05304
0.1 mg

Anti-PDE8A Antibody

Mouse, Rat

$405
Cat # A05304
100ul

PDE8A (NM_002605) Human Over-expression Lysate

Human

$628
Cat # LS005151
100 µg

Anti-PDE8A Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A05304-1
100 µg/vial

PDE8A Overview

Facts about High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A.

PDE8A 3D structure. Source: alphafold

High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (PDE8A)

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:18983167). May be involved in maintaining basal levels of the cyclic nucleotide and/or at the cAMP regulation of germ cell development (PubMed:18983167).

Binding to RAF1 reduces RAF1'Ser- 259' inhibitory-phosphorylation and stimulates RAF1-dependent EGF- activated ERK-signaling (PubMed:23509299). Protects against cell death induced by hydrogen peroxide and staurosporine (PubMed:23509299).

Gene Information

Human
Gene Name:	PDE8A
Uniprot:	O60658
Entrez:	5151

Family

Belongs to:

cyclic nucleotide phosphodiesterase family

Alternative Names

cAMP-specific cyclic nucleotide phosphodiesterase 8A; EC 3.1.4.17; FLJ16150; high affinity cAMP-specific and IBMX-insensitive 3'-5'-cyclic phosphodiesterase8A; high-affinity cAMP-specific and IBMX-insensitive 3'-5'-cyclic phosphodiesterase8A; HsT19550; phosphodiesterase 8A