PDE4C Antibodies

AND PDE4C ELISA kits, PDE4C Proteins

Many biological assays use antibodies to detect PDE4C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDE4C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDE4C antibodies...

We validate the specificity of these antibodies to PDE4C by testing them on tissues known to express PDE4C positively and negatively. Browse below to find the PDE4C antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDE4C Infographic by Boster Bio

All PDE4C Products

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Product

Figures

Specificity

Applications

Price

Anti-PDE4C Antibody

Human, Mouse

$360
Cat # A07630
100 µl

Anti-PDE4C Antibody

5 Q&As

Human, Mouse, Rat

$399
Cat # A07630-1
100μl

Anti-PDE4C Antibody

Human, Mouse, Rat

ICC, WB

$405
Cat # A07630-2
100ul

PDE4C (NM_001098819) Human Over-expression Lysate

Human

$960
Cat # LS005143
100 µg

PDE4C Overview

Facts about cAMP-specific 3',5'-cyclic phosphodiesterase 4C.

PDE4C 3D structure. Source: alphafold

cAMP-specific 3',5'-cyclic phosphodiesterase 4C (PDE4C)

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. .

Gene Information

Human
Gene Name:	PDE4C
Uniprot:	Q08493
Entrez:	5143

Family

Belongs to:

cyclic nucleotide phosphodiesterase family

Alternative Names

cAMP-specific 3'-5'-cyclic phosphodiesterase 4C; DPDE1dunce; Drosophila); EC 3.1.4; EC 3.1.4.17; MGC126222; PDE21; phosphodiesterase 4C, cAMP-specific (dunce (Drosophila)-homologphosphodiesterase E1); phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog; phosphodiesterase 4C, cAMP-specific; phosphodiesterase E1 dunce homolog

Molecular Weight

Mass (kDA):
79.902 kDA

Genomic Context


Human

Location:	19p13.11
Sequence:	19; NC_000019.10 (18207961..18248200, complement)

Tissue Specificity

Expressed in various tissues but not in cells of the immune system.

Subcellular Localizations

Cell projection, cilium.

Diseases

Inflammation
Lung Diseases
Lung Diseases, Obstructive
Chronic Obstructive Airway Disease
Asthma
Vomiting
Autoimmune Diseases
Depressive Disorder
Insulinoma
Pneumonia
Erectile Dysfunction
Autoimmune Reaction

Disease Of Adrenal Medulla
Melanoma
Hypoxia
Respiration Disorders
Airway Obstruction
Fibrosis
Pulmonary Emphysema

Interacting Proteins

Pathways

Secretion
Localization
Reverse Transcription
Insulin Secretion
Pathogenesis
Cell Adhesion
Prepulse Inhibition
Response To Amphetamine
Fibroblast Proliferation
Penile Erection
Protein Secretion
Reflex
Decidualization

Phagocytosis
Cell Cycle
Cellular Localization
Prolactin Secretion
S Phase
Regulation Of Insulin Secretion
Excretion

PTMs

Phosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDE4C

References

PMID: 7843419 by Engels P., et al. Molecular cloning and functional expression in yeast of a human cAMP- specific phosphodiesterase subtype (PDE IV-C).

PMID: 10574328 by Sullivan M., et al. Genomic organisation of the human cyclic AMP-specific phosphodiesterase PDE4C gene and its chromosomal localisation to 19p13.1, between RAB3A and JUND.