PCK1 Antibodies

AND PCK1 ELISA kits, PCK1 Proteins

Many biological assays use antibodies to detect PCK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PCK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PCK1 antibodies...

We validate the specificity of these antibodies to PCK1 by testing them on tissues known to express PCK1 positively and negatively. Browse below to find the PCK1 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PCK1 Infographic by Boster Bio

All PCK1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PCK1 Antibody

Human, Mouse, Rat

$405
Cat # A02022
100ul

Anti-PCK1 Antibody

Human, Mouse, Rat

IP, IF, ICC, WB

$405
Cat # A02022-1
100ul

Anti-PCK1 Antibody

Human

IHC, ICC, WB

$405
Cat # A02022-2
100ul

Anti-PCK1/PEPC Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A02022-3
100 μg/vial

Human PCK1 Recombinant Protein

SDS-PAGE

$265
Cat # PROTP35558
Starting from 10ug

Anti-PCK1 Rabbit Monoclonal Antibody

Human

IHC, WB

$370
Cat # M02022-1
100 μl/vial

PCK1 (NM_002591) Human Over-expression Lysate

Human

$628
Cat # LS005105
100 µg

PCK1 Overview

Facts about Phosphoenolpyruvate carboxykinase, cytosolic [GTP].

PCK1 3D structure. Source: alphafold

Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (PCK1)

Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. .

Gene Information

Human
Gene Name:	PCK1
Uniprot:	P35558
Entrez:	5105

Family

Belongs to:

phosphoenolpyruvate carboxykinase [GTP] family

Alternative Names

EC 4.1.1.32; MGC22652; PCK1; PEPCK1; PEPCKC; PEPCK-C; PEPCK-CPEP carboxykinase; phosphoenolpyruvate carboxykinase 1 (soluble); phosphoenolpyruvate carboxykinase, cytosolic [GTP]; phosphoenolpyruvate carboxykinase, cytosolic; Phosphoenolpyruvate carboxylase; phosphopyruvate carboxylase

Molecular Weight

Mass (kDA):
69.195 kDA

Genomic Context


Human

Location:	20q13.31
Sequence:	20; NC_000020.11 (57561110..57568121)

Tissue Specificity

Major sites of expression are liver, kidney and adipocytes.

Subcellular Localizations

Cytoplasm.

Diseases

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Insulin Resistance
Obesity
Hyperglycemia
Insulin Sensitivity
Liver Carcinoma
Inflammation
Alzheimer's Disease
Dyslipidemias
Impaired Glucose Tolerance
Hypoglycemia

Cholangiocarcinoma
Dysequilibrium Syndrome
Fatty Liver
Hyperinsulinism
Impaired Cognition
Atherosclerosis
Hypertensive Disease

Pathways

Gluconeogenesis
Localization
Pathogenesis
Glucose Homeostasis
Glyoxylate Cycle
Cell Cycle
Glycolysis
Secretion
Urea Cycle
Lipid Homeostasis
Cognition
Mating
Cell Morphogenesis

Lactation
Energy Homeostasis
Dna Replication
Regulation Of Gluconeogenesis
Transport
Aging
Hypersensitivity

PTMs

Phosphorylation
Oxidation
Acetylation
Methylation
Ubiquitination

Carboxylation
Reduction
Deacetylation
Decarboxylation
Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PCK1

References

PMID: 8490617 by Stoffel M., et al. cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to chromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young.

PMID: 8325643 by Ting C.-N., et al. Phosphoenolpyruvate carboxykinase (GTP): characterization of the human PCK1 gene and localization distal to MODY on chromosome 20.