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- Table of Contents
Facts about Protein mono-ADP-ribosyltransferase PARP4.
Human | |
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Gene Name: | PARP4 |
Uniprot: | Q9UKK3 |
Entrez: | 143 |
Belongs to: |
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No superfamily |
193 kDa vault protein; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1; ADPRTL1I-alpha-I-related; EC 2.4.2.30; H5 proline-rich; p193; PARP-4; PARPL; PARP-related; PARP-related/IalphaI-related H5/proline-rich; PH5P; poly (ADP-ribose) polymerase family, member 4; poly [ADP-ribose] polymerase 4; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase-like 1; Vault poly(ADP-ribose) polymerase; vault protein, 193-kDa; VAULT3; von Willebrand factor A domain containing 5C; VPARPKIAA0177; VWA5C
Mass (kDA):
192.595 kDA
Human | |
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Location: | 13q12.12 |
Sequence: | 13; NC_000013.11 (24420930..24512993, complement) |
Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas.
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Also found in the nucleus, associated with mitotic spindles.
PMID: 10477748 by Kickhoefer V.A., et al. The 193 kDa vault protein, VPARP, is a novel poly(ADP-ribose) polymerase.
PMID: 10644454 by Still I.H., et al. Identification of a novel gene (ADPRTL1) encoding a potential poly(ADP-ribosyl)transferase protein.