PARD6G Antibodies

AND PARD6G ELISA kits, PARD6G Proteins

Many biological assays use antibodies to detect PARD6G, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PARD6G in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PARD6G antibodies...

We validate the specificity of these antibodies to PARD6G by testing them on tissues known to express PARD6G positively and negatively. Browse below to find the PARD6G antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PARD6G Infographic by Boster Bio

All PARD6G Products

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Anti-PAR6G PARD6G Antibody

Human, Mouse

ELISA, WB

$380
Cat # A12361
100ul

PARD6G Overview

Facts about Partitioning defective 6 homolog gamma.

PARD6G 3D structure. Source: alphafold

Partitioning defective 6 homolog gamma (PARD6G)

Adapter protein involved in cell cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions.

The PARD6-PARD3 complex links GTP- bound Rho small GTPases to atypical protein kinase C proteins (By similarity). .

Gene Information

Human
Gene Name:	PARD6G
Uniprot:	Q9BYG4
Entrez:	84552

Family

Belongs to:

PAR6 family

Alternative Names

Par-6 (Partitioning Defective 6, C.Elegans) Homolog Gamma; Par-6 Family Cell Polarity Regulator Gamma; PAR-6 Gamma Protein; PAR-6 Gamma; Par-6 Partitioning Defective 6 Homolog Gamma (C. Elegans); Par-6 Partitioning Defective 6 Homolog Gamma; PAR6G; PAR-6G; PAR6gamma; PARD6G; Partitioning Defective 6 Homolog Gamma

Molecular Weight

Mass (kDA):
40.883 kDA

Genomic Context


Human

Location:	18q23
Sequence:	18; NC_000018.10 (80157232..80247514, complement)

Tissue Specificity

Widely expressed, with a higher expression in fetal and adult kidney.

Subcellular Localizations

Cytoplasm. Cell membrane. Cell junction, tight junction.

Diseases

Malignant Neoplasms
Neoplasms
Infective Disorder
Liver Diseases
Liver Carcinoma
Tumor Progression
Malignant Neoplasm Of Breast
Hepatitis
Inflammatory Bowel Diseases
Liver Damage
Hepatitis B
Endometrial Polyp

Intestinal Diseases
Carcinoma
Injury To Liver
Mammary Neoplasms
Endometrial Carcinoma
Liver Cirrhosis
Dysequilibrium Syndrome

Interacting Proteins

CDC42
MARK2
MARK4
PARD3
PRKCI

PRKCZ
RAC1
YWHAH

Pathways

Methylation
Dna Integration
Dna Repair
Dna Methylation
Localization

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PARD6G

References

PMID: 11260256 by Noda Y., et al. Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C.

PMID: 10934474 by Joberty G., et al. The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42.