PAN2 Antibodies

AND PAN2 ELISA kits, PAN2 Proteins

Many biological assays use antibodies to detect PAN2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PAN2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PAN2 antibodies...

We validate the specificity of these antibodies to PAN2 by testing them on tissues known to express PAN2 positively and negatively. Browse below to find the PAN2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PAN2 Infographic by Boster Bio

All PAN2 Products

Product

Figures

Specificity

Applications

Price

PAN2 (NM_014871) Human Recombinant Protein

$1249
Cat # PROTQ504Q3
20 µg

Anti-PAN2 Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A03834-1
100 µg/vial

PAN2 Overview

Facts about PAN2-PAN3 deadenylation complex catalytic subunit PAN2.

PAN2 3D structure. Source: alphafold

PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (PAN2)

Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP).

PAN deadenylation is followed by rapid degradation of the shortened mRNA tails from the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two different mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.

Gene Information

Human
Gene Name:	PAN2
Uniprot:	Q504Q3
Entrez:	9924

Family

Belongs to:

peptidase C19 family

Alternative Names

EC 3.1.13.4; FLJ39360; hPan2; Inactive ubiquitin carboxyl-terminal hydrolase 52; KIAA0710PAB-dependent poly(A)-specific ribonuclease subunit 2; NALP4; PABP-dependent poly(A) nuclease 2; PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae); PAN2 polyA specific ribonuclease subunit; PYPAF4; ubiquitin specific peptidase 52; ubiquitin specific protease 52; USP52