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- Table of Contents
Facts about Polyadenylate-binding protein-interacting protein 2.
Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP construction organization.
Human | |
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Gene Name: | PAIP2 |
Uniprot: | Q9BPZ3 |
Entrez: | 51247 |
Belongs to: |
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PAIP2 family |
MGC72018; PABC1-interacting protein 2; PABP-interacting protein 2; PAIP-2; PAIP2APoly(A)-binding protein-interacting protein 2; poly(A) binding protein interacting protein 2; polyA-binding protein-interacting protein 2; polyadenylate-binding protein-interacting protein 2
Mass (kDA):
14.984 kDA
Human | |
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Location: | 5q31.2 |
Sequence: | 5; NC_000005.10 (139341832..139369720) |
Expressed at highest level in testis, but also abundant in brain, cervix, lung, ovary, placenta, adipose tissue, thymus and thyroid.
Cytoplasm.
PMID: 11172725 by Khaleghpour K., et al. Translational repression by a novel partner of human poly(A) binding protein, Paip2.
PMID: 11438674 by Khaleghpour K., et al. Dual interactions of the translational repressor Paip2 with poly(A) binding protein.