Padi6 Antibodies

AND Padi6 ELISA kits, Padi6 Proteins

Many biological assays use antibodies to detect Padi6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Padi6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Padi6 antibodies...

We validate the specificity of these antibodies to Padi6 by testing them on tissues known to express Padi6 positively and negatively. Browse below to find the Padi6 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Padi6 Infographic by Boster Bio

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PADI6 (NM_207421) Human Over-expression Lysate

Human

$960
Cat # LS353238
100 µg

Padi6 Overview

Facts about Protein-arginine deiminase type-6.

Protein-arginine deiminase type-6 (Padi6)

Catalyzes the deimination of arginine residues of proteins (By similarity). May be involved in cytoskeletal reorganization in the egg and early embryo (PubMed:17587491).

Gene Information

Mouse
Gene Name:	Padi6
Uniprot:	Q8K3V4
Entrez:	242726

Family

Belongs to:

protein arginine deiminase family

Alternative Names

protein-arginine deiminase type-6; hPADVI; peptidyl arginine deiminase, type VI

Molecular Weight

Mass (kDA):
76.778 kDA

Genomic Context


Mouse

Location:	4 D3\|4 72.26 cM
Sequence:	4;

Tissue Specificity

Expressed at very high levels in oocytes. Weakly expressed in testis. Expressed in primordial, primary, secondary and Graafian follicles, and in immature oocytes, mature eggs and blastocyst (at protein level).

Diseases

Arthritis
Rheumatoid Arthritis
Autoimmunity
Basal Cell Carcinoma
Sclerosis
Malignant Squamous Cell Neoplasm
Skin Neoplasms
Myocardial Depression
Melanoma
Heart Failure
Scleroderma
Multiple Sclerosis

Infertility
Degenerative Polyarthritis
Carcinoma
Diffuse Scleroderma
Rheumatism
Fibrosis
Myocarditis

Pathways

Localization
Transport
Chromosome Localization
Translation
Fertilization
Pigmentation
Oocyte Growth
Regulation Of Gene Expression
Histone Modification

Ovulation
Oocyte Maturation
Embryo Development

PTMs

Citrullination
Phosphorylation

Cleavage
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Padi6

References

PMID: 12654293 by Wright P.W., et al. ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase- like protein that localizes to egg cytoplasmic sheets.

PMID: 15087120 by Chavanas S., et al. Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI6.