Pacsin1 Antibodies

AND Pacsin1 ELISA kits, Pacsin1 Proteins

Many biological assays use antibodies to detect Pacsin1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pacsin1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pacsin1 antibodies...

We validate the specificity of these antibodies to Pacsin1 by testing them on tissues known to express Pacsin1 positively and negatively. Browse below to find the Pacsin1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Pacsin1 Infographic by Boster Bio

All Pacsin1 Products

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Product

Figures

Specificity

Applications

Price

PACSIN1 (NM_020804) Human Recombinant Protein

$813
Cat # PROTQ9BY11
20 µg

PACSIN1 (NM_020804) Human Over-expression Lysate

Human

$628
Cat # LS029993
100 µg

Anti-PACSIN1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A06188-2
100 µg/vial

Pacsin1 Overview

Facts about Protein kinase C and casein kinase substrate in neurons protein 1.

Protein kinase C and casein kinase substrate in neurons protein 1 (Pacsin1)

Binds to membranes through its F-BAR domain and mediates membrane tubulation. Plays a role in the reorganization of the microtubule cytoskeleton through its interaction with MAPT; this reduces microtubule stability and inhibits MAPT-induced microtubule polymerization.

Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis through its interaction with COBL and WASL, and by recruiting COBL into the cell cortex.

Gene Information

Mouse
Gene Name:	Pacsin1
Uniprot:	Q61644
Entrez:	23969

Family

Belongs to:

PACSIN family

Alternative Names

KIAA1379SDPI; protein kinase C and casein kinase substrate in neurons 1; protein kinase C and casein kinase substrate in neurons protein 1; syndapin I

Molecular Weight

Mass (kDA):
50.575 kDA

Genomic Context


Mouse

Location:	17\|17 A3.3
Sequence:	17;

Tissue Specificity

Highly expressed in brain. Detected in hippocampus and dorsal root ganglion neurons. Detected in rod photoreceptor terminals in the outer plexiform layer of the retina (at protein level). In CNS neurons, high levels in the pyramidal cells of the hippocampus, Purkinje cells of the cerebellum and large neurons of the cortex and brain stem.