PABPC4 Antibodies

AND PABPC4 ELISA kits, PABPC4 Proteins

Many biological assays use antibodies to detect PABPC4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PABPC4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PABPC4 antibodies...

We validate the specificity of these antibodies to PABPC4 by testing them on tissues known to express PABPC4 positively and negatively. Browse below to find the PABPC4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PABPC4 Infographic by Boster Bio

All PABPC4 Products

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Product

Figures

Specificity

Applications

Price

Anti-PABPC5 PABPC4 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A07960
100ul

Anti-APP-1/PABPC4 Antibody Picoband®

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A07960-2
100 μg/vial

PABPC4 (NM_003819) Human Over-expression Lysate

Human

$960
Cat # LS008761
100 µg

PABPC4 Overview

Facts about Polyadenylate-binding protein 4.

PABPC4 3D structure. Source: alphafold

Polyadenylate-binding protein 4 (PABPC4)

Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism.

Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity). .

Gene Information

Human
Gene Name:	PABPC4
Uniprot:	Q13310
Entrez:	8761

Family

Belongs to:

polyadenylate-binding protein type-1 family

Alternative Names

APP1FLJ43938; APP-1PABP-4; Inducible poly(A)-binding protein; IPABP; iPABPpoly(A)-binding protein, cytoplasmic 4 (inducible form); PABP4Activated-platelet protein 1; poly(A) binding protein, cytoplasmic 4 (inducible form); Poly(A)-binding protein 4; polyadenylate-binding protein 4

Molecular Weight

Mass (kDA):
70.783 kDA

Genomic Context


Human

Location:	1p34.3
Sequence:	1; NC_000001.11 (39560816..39576790, complement)

Tissue Specificity

Expressed at low levels in resting normal T cells; following T-cell activation, however, mRNA levels are rapidly up-regulated.

Subcellular Localizations

Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Diseases

Malignant Neoplasms
Neoplasms
Inflammation
Hyperlipoproteinemias
Coronary Heart Disease
Premature Menopause
Overlying Behavior
Malignant Neoplasm Of Breast
Uterine Cervical Neoplasm
Malignant Tumor Of Cervix
Carcinoma
Invasive Ductal Breast Carcinoma
Cardiovascular Diseases

Invasive Lobular Breast Carcinoma
Mammary Neoplasms
Colorectal Cancer
Carcinoma, Lobular
Medullary Carcinoma Of Breast
Nerve Degeneration
Chronic Inflammation

Interacting Proteins

PHLDA1

Pathways

Translation
Localization
Cell Growth
Cellular Senescence
Immune Response
Regulation Of Gene Expression
Nuclear Export
Senescence
Response To Uv
Cellular Localization

Regulation Of Translation
Pachytene
Pathogenesis
Secretion

PTMs

Isopeptide bond
Methylation

Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PABPC4

References

PMID: 8524242 by Yang H., et al. iPABP, an inducible poly(A)-binding protein detected in activated human T cells.

PMID: 9030741 by Houng A.K., et al. Identification and structure of activated-platelet protein-1, a protein with RNA-binding domain motifs that is expressed by activated platelets.