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- Table of Contents
Facts about Prolyl 4-hydroxylase subunit alpha-3.
Human | |
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Gene Name: | P4HA3 |
Uniprot: | Q7Z4N8 |
Entrez: | 283208 |
Belongs to: |
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P4HA family |
2-oxoglutarate-4-dioxygenase subunit alpha-3; 4-PH alpha-3; alpha polypeptide III; collagen prolyl 4-hydroxylase alpha(III); C-P4H alpha III; C-P4Halpha(III); EC 1.14.11.2; Procollagen-proline; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase); prolyl 4-hydroxylase subunit alpha-3; prolyl 4-hydroxylase, alpha polypeptide III
Mass (kDA):
61.126 kDA
Human | |
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Location: | 11q13.4 |
Sequence: | 11; NC_000011.10 (74259923..74311654, complement) |
Highly expressed in placenta, liver and fetal skin. Weakly expressed in fetal epiphyseal cartilage, fetal liver, fibroblast, lung and skeletal muscle. Expressed also in fibrous cap of carotid atherosclerotic lesions.
Endoplasmic reticulum lumen.
PMID: 14500733 by Kukkola L., et al. Identification and characterization of a third human, rat, and mouse collagen prolyl 4-hydroxylase isoenzyme.
PMID: 12874193 by Van Den Diepstraten C., et al. Cloning of a novel prolyl 4-hydroxylase subunit expressed in the fibrous cap of human atherosclerotic plaque.