P4HA3 Antibodies

AND P4HA3 ELISA kits, P4HA3 Proteins

Many biological assays use antibodies to detect P4HA3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with P4HA3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop P4HA3 antibodies...

We validate the specificity of these antibodies to P4HA3 by testing them on tissues known to express P4HA3 positively and negatively. Browse below to find the P4HA3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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P4HA3 Infographic by Boster Bio

All P4HA3 Products

Product

Figures

Specificity

Applications

Price

Anti-P4HA3 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A10966
100ul

Anti-P4HA3 Mouse Monoclonal Antibody [Clone ID: OTI9A2]

Human, Mouse, Rat

IHC

$523
Cat # M10966
100 µl

P4HA3 (NM_182904) Human Over-expression Lysate

Human

$960
Cat # LS283208
100 µg

P4HA3 Overview

Facts about Prolyl 4-hydroxylase subunit alpha-3.

P4HA3 3D structure. Source: alphafold

Prolyl 4-hydroxylase subunit alpha-3 (P4HA3)

Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. .

Gene Information

Human
Gene Name:	P4HA3
Uniprot:	Q7Z4N8
Entrez:	283208

Family

Belongs to:

P4HA family

Alternative Names

2-oxoglutarate-4-dioxygenase subunit alpha-3; 4-PH alpha-3; alpha polypeptide III; collagen prolyl 4-hydroxylase alpha(III); C-P4H alpha III; C-P4Halpha(III); EC 1.14.11.2; Procollagen-proline; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase); prolyl 4-hydroxylase subunit alpha-3; prolyl 4-hydroxylase, alpha polypeptide III

Molecular Weight

Mass (kDA):
61.126 kDA

Genomic Context


Human

Location:	11q13.4
Sequence:	11; NC_000011.10 (74259923..74311654, complement)

Tissue Specificity

Highly expressed in placenta, liver and fetal skin. Weakly expressed in fetal epiphyseal cartilage, fetal liver, fibroblast, lung and skeletal muscle. Expressed also in fibrous cap of carotid atherosclerotic lesions.

Subcellular Localizations

Endoplasmic reticulum lumen.

Diseases

Burkitt Lymphoma
Hereditary Diseases
Carotid Artery Diseases
Malignant Neoplasm Of Breast
B-cell Lymphomas
Atherosclerosis
Physiological Stress
Endoplasmic Reticulum Stress
Fibrosis

Malignant Neoplasms
Dental Plaque
Arteriosclerosis
Lymphoma

Interacting Proteins

DTNBP1
HGS
MAGEC2
MEOX2
NUTM1

WDR62
ZC3H12A

Pathways

Methylation
Gene Silencing
Dna Methylation

PTMs

Hydroxylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/P4HA3

References

PMID: 14500733 by Kukkola L., et al. Identification and characterization of a third human, rat, and mouse collagen prolyl 4-hydroxylase isoenzyme.

PMID: 12874193 by Van Den Diepstraten C., et al. Cloning of a novel prolyl 4-hydroxylase subunit expressed in the fibrous cap of human atherosclerotic plaque.