P4HA1 Antibodies

AND P4HA1 ELISA kits, P4HA1 Proteins

Many biological assays use antibodies to detect P4HA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with P4HA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop P4HA1 antibodies...

We validate the specificity of these antibodies to P4HA1 by testing them on tissues known to express P4HA1 positively and negatively. Browse below to find the P4HA1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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P4HA1 Infographic by Boster Bio

All P4HA1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-P4HA1 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A05917
100ul

P4HA1 (NM_000917) Human Recombinant Protein

$1062
Cat # PROTP13674
20 µg

P4HA1 (NM_000917) Human Over-expression Lysate

Human

$960
Cat # LS005033
100 µg

P4HA1 Overview

Facts about Prolyl 4-hydroxylase subunit alpha-1.

P4HA1 3D structure. Source: alphafold

Prolyl 4-hydroxylase subunit alpha-1 (P4HA1)

Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. .

Gene Information

Human
Gene Name:	P4HA1
Uniprot:	P13674
Entrez:	5033

Family

Belongs to:

P4HA family

Alternative Names

2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase); 2-oxoglutarate-4-dioxygenase subunit alpha-1; 4-PH alpha-1; alpha polypeptide I; EC 1.14.11.2; Procollagen-proline; prolyl 4-hydroxylase, alpha polypeptide I

Molecular Weight

Mass (kDA):
61.049 kDA

Genomic Context


Human

Location:	10q22.1
Sequence:	10; NC_000010.11 (73007217..73096974, complement)

Subcellular Localizations

Endoplasmic reticulum lumen.

Diseases

Hypoxia
Dental Plaque
Anoxia
Inflammation
Aneurysm
Malignant Neoplasm Of Breast
Malignant Neoplasms
Mammary Neoplasms
Hereditary Diseases
Aortic Aneurysm
Liver Diseases
Reperfusion Injury

Burkitt Lymphoma
Von Hippel-lindau Syndrome
Degenerative Polyarthritis
Endoplasmic Reticulum Stress
Alcoholic Liver Diseases
Cardiovascular Diseases
Neoplasms

Interacting Proteins

Pathways

Localization
Methylation
Pathogenesis
Secretion
Transport
Cell Proliferation
Oxygen Homeostasis
Response To Hypoxia
Dna Methylation
Energy Homeostasis

Demethylation
Drug Resistance
Rna Interference
Cellular Response To Hypoxia
Nuclear Import

PTMs

Hydroxylation
Demethylation

Phosphorylation
Acetylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/P4HA1

References

PMID: 2543975 by Helaakoski T., et al. Molecular cloning of the alpha-subunit of human prolyl 4-hydroxylase: the complete cDNA-derived amino acid sequence and evidence for alternative splicing of RNA transcripts.

PMID: 7961714 by Helaakoski T., et al. Structure and expression of the human gene for the alpha subunit of prolyl 4-hydroxylase. The two alternatively spliced types of mRNA correspond to two homologous exons the sequences of which are expressed in a variety of tissues.