P2X purinoceptor 2 (P2RX2)

Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, understanding of flavor and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, internal ear gap junctions, and K(+) recycling.

Mediates synaptic transmission between neurons and from neurons to smooth muscle. .