TRIM32 Antibodies

AND TRIM32 ELISA kits, TRIM32 Proteins

Many biological assays use antibodies to detect TRIM32, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRIM32 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRIM32 antibodies...

We validate the specificity of these antibodies to TRIM32 by testing them on tissues known to express TRIM32 positively and negatively. Browse below to find the TRIM32 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRIM32 Infographic by Boster Bio

All TRIM32 Products

Product

Figures

Specificity

Applications

Price

TRIM32 (NM_001099679) Human Recombinant Protein

$1249
Cat # PROTQ13049
20 µg

TRIM32 (NM_012210) Human Over-expression Lysate

Human

$628
Cat # LS022954
100 µg

TRIM32 Overview

Facts about E3 ubiquitin-protein ligase TRIM32.

TRIM32 3D structure. Source: alphafold

E3 ubiquitin-protein ligase TRIM32 (TRIM32)

Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation.

May ubiquitinate BBS2. May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo.

Gene Information

Human
Gene Name:	TRIM32
Uniprot:	Q13049
Entrez:	22954

Family

Belongs to:

TRIM/RBCC family

Alternative Names

72 kDa Tat-interacting protein; BBS11; BBS1172-KD; EC 6.3.2.-; HT2A; HT2Alimb girdle muscular dystrophy 2H (autosomal recessive); LGMD2H; TATIP; TRIM32; tripartite motif containing 32; Zinc finger protein HT2A; zinc-finger protein HT2A

Molecular Weight

Mass (kDA):
71.989 kDA

Genomic Context


Human

Location:	9q33.1
Sequence:	9; NC_000009.12 (116687302..116701300)

Tissue Specificity

Spleen, thymus, prostate, testis, ovary, intestine, colon and skeletal muscle.

Subcellular Localizations

Cytoplasm. Localized in cytoplasmic bodies, often located around the nucleus.

Diseases

Muscular Dystrophy
Dystrophy
Muscular Dystrophies, Limb-girdle
Sarcotubular Myopathy
Myopathy
Bardet-biedl Syndrome
Lymphoma, Non-hodgkin
Carcinoma
Neoplasms
Carcinogenesis
Cell Transformation, Neoplastic
Malignant Neoplasms
Weakness

Muscular Atrophy
Polydactyly
Atrophy
Malignant Squamous Cell Neoplasm
Obesity
Leukemia
Neoplasm Metastasis

Interacting Proteins

ABI2
ATXN1
CLIP4
KCTD9
PDE9A

PTPN11
RABAC1
SCGB1A1
SDCBP
TRIM5

UBE2N
UBE2U
UBE2V1
UBQLN1
UBQLN2

UBQLN4

Pathways

Pathogenesis
Transport
Cell Migration
Gene Silencing
Cell Proliferation
Muscle Atrophy
Localization
Senescence
Regeneration
Cell Adhesion
Stem Cell Differentiation
Cell Division
Asymmetric Cell Division

Sensitization
Response To Uv
Cell Motility
Cell Differentiation
Oncogenesis
Mitosis
Glycosylation

PTMs

Ubiquitination
Sumoylation

Cleavage
Glycosylation

Phosphorylation

Research Areas

Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRIM32

References

PMID: 7778269 by Fridell R.A., et al. Identification of a novel human zinc finger protein that specifically interacts with the activation domain of lentiviral Tat proteins.

PMID: 19349376 by Locke M., et al. TRIM32 is an E3 ubiquitin ligase for dysbindin.