OSMR Antibodies

AND OSMR ELISA kits, OSMR Proteins

Many biological assays use antibodies to detect OSMR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with OSMR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop OSMR antibodies...

We validate the specificity of these antibodies to OSMR by testing them on tissues known to express OSMR positively and negatively. Browse below to find the OSMR antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OSMR Infographic by Boster Bio

All OSMR Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Osmr Antibody Picoband®

Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A04061-2
100 µg/vial

Human OSMR ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2268
96 wells/kit, with removable strips.

Human OSMRb ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2282
96 wells/kit, with removable strips.

OSMR Overview

Facts about Oncostatin-M-specific receptor subunit beta.

OSMR 3D structure. Source: alphafold

Oncostatin-M-specific receptor subunit beta (OSMR)

Associates with IL31RA to form the IL31 receptor.
Binds IL31 to activate STAT3 and possibly STAT1 and STAT5.

Capable of transducing OSM-specific signaling events. .

Gene Information

Human
Gene Name:	OSMR
Uniprot:	Q99650
Entrez:	9180

Family

Belongs to:

type I cytokine receptor family

Alternative Names

IL-31 receptor subunit beta; IL-31R subunit beta; IL-31RB; IL-31R-beta; Interleukin-31 receptor subunit beta; MGC150627; MGC75127; oncostatin M receptor; oncostatin-M specific receptor beta subunit; oncostatin-M-specific receptor subunit beta; OSM R beta; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1

Molecular Weight

Mass (kDA):
110.509 kDA

Genomic Context


Human

Location:	5p13.1
Sequence:	5; NC_000005.10 (38845858..38945579)

Tissue Specificity

Expressed in keratinocytes (at protein level) (PubMed:21261663). Expressed at relatively high levels in all neural cells as well as fibroblast and epithelial cells (PubMed:8999038).

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Leukemia
Neoplasms
Malignant Neoplasms
Janiceps
Inflammation
Amyloidosis
Carcinoma
Pruritus
Cutaneous Amyloidosis
Amyloidosis, Familial
Tissue Adhesions
Dermatologic Disorders
Liver Carcinoma

Dermatitis, Atopic
Dermatitis
Melanoma
Colorectal Cancer
Colorectal Neoplasms
Tumor Angiogenesis
Uterine Cervical Neoplasm

Interacting Proteins

IL6ST

Pathways

Cell Proliferation
Cell Adhesion
Methylation
Osteoblast Differentiation
Dna Methylation
Cell Growth
Angiogenesis
Rna Interference
Bone Resorption
Cell Motility
Cell Cycle
Liver Regeneration
Regeneration

Cytokine Production
Pathogenesis
Secretion
Osteoclast Differentiation
Cell Migration
Osteoblast Development
Tube Formation

PTMs

Phosphorylation
Methylation
Cleavage

Deacetylation
Acetylation
Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OSMR

References

PMID: 8999038 by Mosley B., et al. Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation.

PMID: 15184896 by Dillon S.R., et al. Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice.