OAS2 Antibodies

AND OAS2 ELISA kits, OAS2 Proteins

Many biological assays use antibodies to detect OAS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with OAS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop OAS2 antibodies...

We validate the specificity of these antibodies to OAS2 by testing them on tissues known to express OAS2 positively and negatively. Browse below to find the OAS2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OAS2 Infographic by Boster Bio

All OAS2 Products

Product

Figures

Specificity

Applications

Price

Anti-OAS2 Antibody

Human

ELISA, IHC, WB

$380
Cat # A01878
100ul

Anti-OAS2 Mouse Monoclonal Antibody [Clone ID: OTI6E6]

Human

IHC, WB

$523
Cat # M01878
100 µl

OAS2 (NM_002535) Human Over-expression Lysate

Human

$628
Cat # LS004939
100 µg

OAS2 Overview

Facts about 2'-5'-oligoadenylate synthase 2.

OAS2 3D structure. Source: alphafold

2'-5'-oligoadenylate synthase 2 (OAS2)

Interferon-induced, dsRNA-activated antiviral receptor that plays a vital role in cellular innate antiviral response (PubMed:10464285, PubMed:9880569). Activated by detection of double stranded RNA (dsRNA): polymerizes higher oligomers of 2'- 5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNASEL) leading to its dimerization and subsequent activation (PubMed:10464285, PubMed:9880569, PubMed:11682059).

Activation of RNASEL leads to degradation of cellular as well as viral RNA, leading to the inhibition of protein synthesis, thus terminating viral replication (PubMed:10464285, PubMed:9880569). Can mediate the antiviral effect via the classical RNASEL-dependent pathway or another antiviral pathway independent of RNASEL (PubMed:21142819).

Gene Information

Human
Gene Name:	OAS2
Uniprot:	P29728
Entrez:	4939

Family

Belongs to:

2-5A synthase family

Alternative Names

(2-5')oligo(A) synthase 2; (2'-5')oligo(A) synthetase 2; (2-5')oligo(A) synthetase 2; 2'5' oligoadenylate synthetase 2; 2-5A synthase 2; 2-5A synthetase 2; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2 (69-71 kD); 2'-5'-oligoadenylate synthetase 2, 69/71kDa; EC 2.7.7; EC 2.7.7.-; MGC78578; OAS2; p69 OAS / p71 OAS; p69OAS / p71OAS