Proton channel OTOP2 Antibodies

AND OTOP2 ELISA kits, Proton channel OTOP2 Proteins

Many biological assays use antibodies to detect Proton channel OTOP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Proton channel OTOP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Proton channel OTOP2 antibodies...

We validate the specificity of these antibodies to Proton channel OTOP2 by testing them on tissues known to express OTOP2 positively and negatively. Browse below to find the OTOP2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OTOP2 Infographic by Boster Bio

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OTOP2 (NM_178160) Human Over-expression Lysate

Human

$960
Cat # LS092736
100 µg

OTOP2 Overview

Facts about Proton channel OTOP2.

OTOP2 3D structure. Source: alphafold

Proton channel OTOP2 (OTOP2)

Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes.

Gene Information

Human
Gene Name:	OTOP2
Uniprot:	Q7RTS6
Entrez:	92736

Family

Belongs to:

otopetrin family

Alternative Names

otopetrin 2; otopetrin-2

Molecular Weight

Mass (kDA):
62.236 kDA

Genomic Context


Human

Location:	17q25.1
Sequence:	17; NC_000017.11 (74922955..74933913)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Usher Syndrome
Congenital Absence
Complete Hearing Loss
Macule
Vestibular Diseases

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OTOP2

References

PMID: 12651873 by Hurle B., et al. Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1.