Optic atrophy 3 protein Antibodies

AND OPA3 ELISA kits, Optic atrophy 3 protein Proteins

Many biological assays use antibodies to detect Optic atrophy 3 protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Optic atrophy 3 protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Optic atrophy 3 protein antibodies...

We validate the specificity of these antibodies to Optic atrophy 3 protein by testing them on tissues known to express OPA3 positively and negatively. Browse below to find the OPA3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OPA3 Infographic by Boster Bio

All OPA3 Products

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Product

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Specificity

Applications

Price

Anti-Optic atrophy 3 protein OPA3 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A06345
100ul

OPA3 (NM_025136) Human Recombinant Protein

$1249
Cat # PROTQ9H6K4
20 µg

Anti-OPA3 Mouse Monoclonal Antibody [Clone ID: OTI3G4]

Human

IHC, WB

$523
Cat # M06345
100 µl

OPA3 (NM_025136) Human Over-expression Lysate

Human

$628
Cat # LS080207
100 µg

Anti-OPA3 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A06345-1
100 µg/vial

OPA3 Overview

Facts about Optic atrophy 3 protein.

OPA3 3D structure. Source: alphafold

Optic atrophy 3 protein (OPA3)

May play some role in mitochondrial processes. .

Gene Information

Human
Gene Name:	OPA3
Uniprot:	Q9H6K4
Entrez:	80207

Family

Belongs to:

OPA3 family

Alternative Names

FLJ22187; FLJ25932; MGA3Optic atrophy 3 (Iraqi-Jewish 'optic atrophy plus'); MGC75494; optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia); optic atrophy 3 protein

Molecular Weight

Mass (kDA):
19.996 kDA

Genomic Context


Human

Location:	19q13.32
Sequence:	19; NC_000019.10 (45527427..45584802, complement)

Tissue Specificity

Ubiquitous. Most prominent expression in skeletal muscle and kidney.

Subcellular Localizations

Mitochondrion.

Diseases

Optic Atrophy
Atrophy
Optic Atrophy, Autosomal Dominant
Disorder Of The Optic Nerve
3-@methylglutaconic Aciduria, Type I
Optic Atrophy, Hereditary, Leber
3-methylglutaconic Aciduria Type 3
Cataract
Ataxia
Mitochondrial Diseases
Optic Atrophies, Hereditary
Muscle Spasticity

Sensorineural Hearing Loss (disorder)
Visual Impairment
Chorea
Inborn Errors Of Metabolism
Spastic Paraplegia, Hereditary
Cardiomyopathies

Pathways

Excretion
Transport
Oxidative Phosphorylation
Localization
Cell Death
Pathogenesis
Mitochondrial Fusion
Intracellular Transport
Electron Transport

Mitochondrial Fission
Electron Transport Chain
Lipid Storage

PTMs

Phosphorylation

Reduction

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OPA3

References

PMID: 11668429 by Anikster Y., et al. Type III 3-methylglutaconic aciduria (optic atrophy plus syndrome, or Costeff optic atrophy syndrome): identification of the OPA3 gene and its founder mutation in Iraqi Jews.

PMID: 15342707 by Reynier P., et al. OPA3 gene mutations responsible for autosomal dominant optic atrophy and cataract.