OGDH Antibodies

AND OGDH ELISA kits, OGDH Proteins

Many biological assays use antibodies to detect OGDH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with OGDH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop OGDH antibodies...

We validate the specificity of these antibodies to OGDH by testing them on tissues known to express OGDH positively and negatively. Browse below to find the OGDH antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: OPHN1

OGDH Infographic by Boster Bio

All OGDH Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-OGDH Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A05301
100ul

OGDH (NM_002541) Human Over-expression Lysate

Human

$628
Cat # LS004967
100 µg

Anti-OGDH Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A05301-1
100 µg/vial

OGDH Overview

Facts about 2-oxoglutarate dehydrogenase, mitochondrial.

OGDH 3D structure. Source: alphafold

2-oxoglutarate dehydrogenase, mitochondrial (OGDH)

2-oxoglutarate dehydrogenase (E1) component of the 2- oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate (PubMed:24495017). The 2- oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) (PubMed:24495017).

The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion (PubMed:29211711). A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is necessary for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (PubMed:29211711).

Gene Information

Human
Gene Name:	OGDH
Uniprot:	Q02218
Entrez:	4967

Family

Belongs to:

alpha-ketoglutarate dehydrogenase family

Alternative Names

2-oxoglutarate dehydrogenase complex component E1; 2-oxoglutarate dehydrogenase, mitochondrial; AKGDH; alpha KGD; alpha-KGD; E1k; OGDC; oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide); oxoglutarate decarboxylase; oxoglutarate dehydrogenase (succinyl-transferring)

Molecular Weight

Mass (kDA):
115.935 kDA

Genomic Context


Human

Location:	7p13
Sequence:	7; NC_000007.14 (44606572..44709066)

Subcellular Localizations

Mitochondrion matrix. Nucleus. Mainly localizes in the mitochondrion. A small fraction localizes to the nucleus, where the 2-oxoglutarate dehydrogenase complex is required for histone succinylation.