Obscurin Antibodies

AND OBSCN ELISA kits, Obscurin Proteins

Many biological assays use antibodies to detect Obscurin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Obscurin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Obscurin antibodies...

We validate the specificity of these antibodies to Obscurin by testing them on tissues known to express OBSCN positively and negatively. Browse below to find the OBSCN antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OBSCN Infographic by Boster Bio

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OBSCN Overview

Facts about Obscurin.

Obscurin (OBSCN)

Structural component of striated muscles that plays a role in myofibrillogenesis. Probably involved in the assembly of myosin to sarcomeric A groups in striated muscle (PubMed:11448995, PubMed:16205939).

Has serine/threonine protein kinase activity and phosphorylates N-cadherin CDH2 and sodium/potassium-transporting ATPase subunit ATP1B1 (By similarity). .

Gene Information

Human
Gene Name:	OBSCN
Uniprot:	Q5VST9
Entrez:	84033

Family

Belongs to:

protein kinase superfamily

Alternative Names

ARHGEF30; DKFZp666E245; EC 2.7.11.1; FLJ14124; KIAA1556MGC120412; KIAA1639MGC138590; MGC120409; MGC120410; MGC120411; obscurin; obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF; obscurin, myosin light chain kinase; obscurin-MLCK; Obscurin-myosin light chain kinase; obscurin-RhoGEF; UNC89

Molecular Weight

Mass (kDA):
868.484 kDA

Genomic Context


Human

Location:	1q42.13
Sequence:	1; NC_000001.11 (228208044..228378874)

Subcellular Localizations

[Isoform 3]: Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, myofibril, sarcomere, Z line. In differentiating skeletal muscle cells, isoform 3 primarily localizes to the sarcomeric M-line and less frequently to the Z-disk (PubMed:12527750). Isoform 3 colocalizes with ANK1 isoform Mu17/ank1.5 at the M-line in differentiated skeletal muscle cells (PubMed:12527750).; Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, myofibril, sarcomere, Z line. Cell membrane, sarcolemma. Nucleus. Colocalizes with CDH2 and ATP1B1 to the sarcolemma and to intercalating disks in cardiac muscles. Colocalizes w