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- Table of Contents
Facts about Ornithine decarboxylase antizyme 3.
Doesn't target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity (PubMed:17900240). Stabilizes AZIN2 by interfering with its ubiquitination.
Human | |
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Gene Name: | OAZ3 |
Uniprot: | Q9UMX2 |
Entrez: | 51686 |
Belongs to: |
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ODC antizyme family |
antizyme 3; AZ3; OAZ-t; ODC-Az 3; ornithine decarboxylase antizyme 3; TISP15
Mass (kDA):
27.413 kDA
Human | |
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Location: | 1q21.3 |
Sequence: | 1; NC_000001.11 (151762969..151771330) |
Testis specific.
Nucleus. Cytoplasm.
PMID: 10781085 by Ivanov I.P., et al. Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: antizyme 3.
PMID: 17900240 by Kanerva K., et al. Human ornithine decarboxylase paralogue (ODCp) is an antizyme inhibitor but not an arginine decarboxylase.