NUP50 Antibodies

AND NUP50 ELISA kits, NUP50 Proteins

Many biological assays use antibodies to detect NUP50, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NUP50 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NUP50 antibodies...

We validate the specificity of these antibodies to NUP50 by testing them on tissues known to express NUP50 positively and negatively. Browse below to find the NUP50 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NUP50 Infographic by Boster Bio

All NUP50 Products

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Product

Figures

Specificity

Applications

Price

NUP50 (NM_153645) Human Recombinant Protein

$1062
Cat # PROTQ9UKX7
20 µg

Anti-NUP50 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # M06152
100 μl/vial

Anti-NUP50 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M06152-1
100 μl/vial

NUP50 (NM_007172) Human Over-expression Lysate

Human

$628
Cat # LS010762
100 µg

NUP50 Overview

Facts about Nuclear pore complex protein Nup50.

NUP50 3D structure. Source: alphafold

Nuclear pore complex protein Nup50 (NUP50)

Component of the nuclear pore complex which has a direct role in nuclear protein import (PubMed:20016008). Actively displaces NLSs from importin-alpha, and facilitates disassembly of this importin-alpha:beta-cargo complex and importin recycling (PubMed:20016008).

Interacts with regulatory proteins of cell cycle progression including CDKN1B (By similarity). This interaction is required for correct intracellular transport and degradation of CDKN1B (By similarity).

Gene Information

Human
Gene Name:	NUP50
Uniprot:	Q9UKX7
Entrez:	10762

Family

Belongs to:

No superfamily

Alternative Names

50 kDa nucleoporin; MGC39961; NPAP60; NPAP60LNucleoporin Nup50; nuclear pore complex protein Nup50; Nuclear pore-associated protein 60 kDa-like; nuclear pore-associated protein 60L; nucleoporin 50kD; nucleoporin 50kDa

Molecular Weight

Mass (kDA):
50.144 kDA

Genomic Context


Human

Location:	22q13.31
Sequence:	22; NC_000022.11 (45163925..45188017)

Tissue Specificity

Ubiquitous. Highest levels in testis, peripheral blood leukocytes and fetal liver.

Subcellular Localizations

Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Localizes to the nucleoplasmic fibrils of the nuclear pore complex (By similarity). Dissociates from the NPC structure early during prophase of mitosis (PubMed:12802065). Associates with the newly formed nuclear membrane during telophase (PubMed:12802065). In the testis, the localization changes during germ cell differentiation from the nuclear surface in spermatocytes to the whole nucleus (interior) in spermatids and back to the nuclear surface in spermatozoa (By similarity).