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NTSR1 Antibodies

AND NTSR1 ELISA kits, NTSR1 Proteins

Many biological assays use antibodies to detect NTSR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NTSR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NTSR1 antibodies...

We validate the specificity of these antibodies to NTSR1 by testing them on tissues known to express NTSR1 positively and negatively. Browse below to find the NTSR1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NTSR1 Infographic by Boster Bio

NTSR1 protein infographic

All NTSR1 Products

Product

Figures

Specificity

Applications

Price

Anti-NTR1 (H218) NTSR1 Antibody

Human, Mouse

IF, IHC, WB

$405
Cat # A04610-3
100ul

Anti-Neurotensin Receptor 1/NTSR1 Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A04610-4
100 μg/vial

Neurotensin Receptor 1 (NTSR1) (NM_002531) Human Over-expression Lysate

Human

$960
Cat # LS004923
100 µg

NTSR1 Overview

Facts about Neurotensin receptor type 1.

NTSR1 3D structure

NTSR1 3D structure. Source: alphafold

Neurotensin receptor type 1 (NTSR1)

G-protein coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:8381365, PubMed:21725197, PubMed:23140271). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system.

Signaling leads to the activation of downstream MAP kinases and protects cells from apoptosis (PubMed:21725197). .

Gene Information

Human
Gene Name:	NTSR1
Uniprot:	P30989
Entrez:	4923

Gene Information

Family

Belongs to:

G-protein coupled receptor 1 family

Family

Alternative Names

NTR1; NTRH; NTRR; NTS1; NTSR1

Molecular Weight

Mass (kDA):
46.259 kDA

Molecular Weight

Genomic Context


Human

Location:	20q13.33
Sequence:	20; NC_000020.11 (62708770..62762771)

Tissue Specificity

Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Membrane raft. Palmitoylation is required for localization at CAV1-enriched membrane rafts.

Subcellular Localization

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Malignant Neoplasm Of Breast
Neoplasm Invasiveness
Malignant Paraganglionic Neoplasm
Cell Invasion
Neoplasm Metastasis
Malignant Tumor Of Colon
Mammary Neoplasms
Adenocarcinoma

Tumor Progression
Colonic Neoplasms
Nervousness
Malignant Squamous Cell Neoplasm
Adenoma
Dysequilibrium Syndrome

Disease

Interacting Proteins

DRD2
NTS

Interacting Proteins

Pathways

Cell Proliferation
Secretion
Insulin Secretion
Fertilization
Intracellular Signal Transduction
Behavioral Fear Response
Energy Homeostasis
Methylation
Gastric Emptying
Feeding Behavior

Cell Growth
Wound Healing
Pathogenesis
Fear Response

Pathways

PTMs

Demethylation
Phosphorylation

Methylation
Acylation

Research Areas

GPCR

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NTSR1

References

PMID: 8381365 by Vita N., et al. Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor.

PMID: 20048080 by Swift S.L., et al. Altered expression of neurotensin receptors is associated with the differentiation state of prostate cancer.