NPY2R Antibodies

AND NPY2R ELISA kits, NPY2R Proteins

Many biological assays use antibodies to detect NPY2R, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NPY2R in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NPY2R antibodies...

We validate the specificity of these antibodies to NPY2R by testing them on tissues known to express NPY2R positively and negatively. Browse below to find the NPY2R antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NPY2R Infographic by Boster Bio

All NPY2R Products

Product

Figures

Specificity

Applications

Price

Anti-NPY Y2 Receptor Npy2r Antibody

Mouse, Rat

IF, IHC, WB

$445
Cat # A04721Y2
100 ul

Anti-NPY2-R Antibody

Human, Mouse, Rat

ELISA, IF, WB

$380
Cat # A04721-1
100ul

Anti-NPY2R Antibody (N-term)

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$298
Cat # M04721
80 µl

NPY2R Overview

Facts about Neuropeptide Y receptor type 2.

NPY2R 3D structure. Source: alphafold

Neuropeptide Y receptor type 2 (NPY2R)

Receptor for neuropeptide Y and peptide YY.
The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.

Gene Information

Human
Gene Name:	NPY2R
Uniprot:	P49146
Entrez:	4887

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

neuropeptide Y receptor type 2; neuropeptide Y receptor Y2; NPY2R; NPY2-R; NPY-Y2 receptor; Y2 Receptor

Molecular Weight

Mass (kDA):
42.731 kDA

Genomic Context


Human

Location:	4q32.1
Sequence:	4; NC_000004.12 (155173723..155217076)

Tissue Specificity

High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Obesity
Dysequilibrium Syndrome
Cholangiocarcinoma
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Metabolic Syndrome X
Hypertensive Disease
Disease Of Adrenal Medulla
Tobacco Dependence Syndrome
Diabetic Macular Edema
Tumor Angiogenesis

Tobacco Use Disorder
Retinal Diseases
Pathologic Vasoconstriction
Diabetic Retinopathy
Chromosomal Duplication

Interacting Proteins

Pathways

Feeding Behavior
Response To Stress
Vasoconstriction
Regulation Of Feeding Behavior
Angiogenesis
Developmental Maturation
Energy Homeostasis
Localization

Reflex
Secretion

PTMs

Disulfide bond
Glycoprotein

Lipoprotein
Palmitate

Research Areas

GPCR
Neuroscience
Neurotransmission

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NPY2R

References

PMID: 7592910 by Gerald C., et al. Expression cloning and pharmacological characterization of a human hippocampal neuropeptide Y/peptide YY Y2 receptor subtype.

PMID: 8632753 by Gehlert D.R., et al. Expression cloning of a human brain neuropeptide Y Y2 receptor.