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- Table of Contents
Facts about NFAT activation molecule 1.
May be involved in the regulation of B-cell, but not T-cell, development. .
Mouse | |
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Gene Name: | Nfam1 |
Uniprot: | Q8R4V1 |
Entrez: | 74039 |
Belongs to: |
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No superfamily |
calcinerin/NFAT-activating ITAM-containing protein; Calcineurin/NFAT-activating ITAM-containing protein; CNAIP; CNAIPbK126B4.4; FLJ40652; NFAM1; NFAT activating protein with ITAM motif 1; NFAT activation molecule 1; NFAT-activating protein with ITAM motif 1
Mass (kDA):
29.988 kDA
Mouse | |
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Location: | 15|15 E1 |
Sequence: | 15; |
Highly expressed in the spleen, expressed by both B- and CD4+ and CD8+ T-cells, as well as non-T- and non-B- cells, including macrophages and neutrophils. Expressed at low levels, if any, in non-immune tissue.
PMID: 15143214 by Ohtsuka M., et al. NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling.