Nfam1 Antibodies

AND Nfam1 ELISA kits, Nfam1 Proteins

Many biological assays use antibodies to detect Nfam1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nfam1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nfam1 antibodies...

We validate the specificity of these antibodies to Nfam1 by testing them on tissues known to express Nfam1 positively and negatively. Browse below to find the Nfam1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Nfam1 Infographic by Boster Bio

All Nfam1 Products

Product

Figures

Specificity

Applications

Price

Anti-NFAT activation molecule 1 NFAM1 Antibody

Human

ELISA, WB

$380
Cat # A10383
100ul

NFAM1 (NM_145912) Human Over-expression Lysate

Human

$628
Cat # LS150372
100 µg

Nfam1 Overview

Facts about NFAT activation molecule 1.

NFAT activation molecule 1 (Nfam1)

May function in immune system for a receptor that activates via the calcineurin/NFAT-signaling pathway that the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters (By similarity).

May be involved in the regulation of B-cell, but not T-cell, development. .

Gene Information

Mouse
Gene Name:	Nfam1
Uniprot:	Q8R4V1
Entrez:	74039

Family

Belongs to:

No superfamily

Alternative Names

calcinerin/NFAT-activating ITAM-containing protein; Calcineurin/NFAT-activating ITAM-containing protein; CNAIP; CNAIPbK126B4.4; FLJ40652; NFAM1; NFAT activating protein with ITAM motif 1; NFAT activation molecule 1; NFAT-activating protein with ITAM motif 1

Molecular Weight

Mass (kDA):
29.988 kDA

Genomic Context


Mouse

Location:	15\|15 E1
Sequence:	15;

Tissue Specificity

Highly expressed in the spleen, expressed by both B- and CD4+ and CD8+ T-cells, as well as non-T- and non-B- cells, including macrophages and neutrophils. Expressed at low levels, if any, in non-immune tissue.

Diseases

Malignant Neoplasms
Inflammation
Regurgitation
Malignant Neoplasm Of Breast
Polyps
Dermatitis, Atopic
Malignant Tumor Of Colon
Malignant Neoplasm Of Liver
Sarcoma
Degenerative Polyarthritis
Immunologic Deficiency Syndromes
Congenital Heart Defects

Neoplasms
Asthma
Peripheral Circulatory Failure
Mammary Neoplasms
Chimera Disorder
Rheumatoid Arthritis
Esophageal Neoplasms

Pathways

Cytokine Production
Translation
Cell Cycle
Cell Development
Pathogenesis
Viral Replication

Localization

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nfam1

References

PMID: 15143214 by Ohtsuka M., et al. NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling.