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- Table of Contents
Facts about Nanos homolog 3.
Maintains the germ cell lineage by curbing both Bax- dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.
Mouse | |
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Gene Name: | Nanos3 |
Uniprot: | P60324 |
Entrez: | 244551 |
Belongs to: |
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nanos family |
MGC120114; nanos homolog 3 (Drosophila); nanos homolog 3; NOS-3; NOS3NANOS1L
Mass (kDA):
19.241 kDA
Mouse | |
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Location: | 8|8 C2 |
Sequence: | 8; |
Expressed in undifferentiated spermatogonial cells.
PMID: 12947200 by Tsuda M., et al. Conserved role of nanos proteins in germ cell development.
PMID: 17138666 by Suzuki A., et al. Functional redundancy among Nanos proteins and a distinct role of Nanos2 during male germ cell development.