NUP85 Antibodies

AND NUP85 ELISA kits, NUP85 Proteins

Many biological assays use antibodies to detect NUP85, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NUP85 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NUP85 antibodies...

We validate the specificity of these antibodies to NUP85 by testing them on tissues known to express NUP85 positively and negatively. Browse below to find the NUP85 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NUP85 Infographic by Boster Bio

All NUP85 Products

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Product

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Specificity

Applications

Price

Anti-NUP85 Antibody

Human, Mouse, Rat

$405
Cat # A07147
100ul

Pericentrin 1 (NUP85) (NM_024844) Human Over-expression Lysate

Human

$628
Cat # LS079902
100 µg

NUP85 Overview

Facts about Nuclear pore complex protein Nup85.

NUP85 3D structure. Source: alphafold

Nuclear pore complex protein Nup85 (NUP85)

Essential component of the nuclear pore complex (NPC) that seems to be needed for NPC assembly and maintenance (PubMed:12718872). Included in the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP96/Nup98 and NUP153 to the nucleus (PubMed:12718872).

The Nup107-160 complex seems to be necessary for spindle assembly during mitosis (PubMed:16807356). NUP85 is necessary for membrane clustering of CCL2-activated CCR2 (PubMed:15995708).

Gene Information

Human
Gene Name:	NUP85
Uniprot:	Q9BW27
Entrez:	79902

Family

Belongs to:

nucleoporin Nup85 family

Alternative Names

85 kDa nucleoporin; FLJ12549; FROUNT; nuclear pore complex protein Nup85; nucleoporin 85kDa; Nucleoporin Nup75; Nucleoporin Nup85; Nucleoporin; Nup75; NUP85; PCNT; PCNT1; Pericentrin-1

Molecular Weight

Mass (kDA):
75.019 kDA

Genomic Context


Human

Location:	17q25.1
Sequence:	17; NC_000017.11 (75205436..75235759)

Subcellular Localizations

Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Nucleus membrane. During mitosis, localizes to the kinetochores and spindle poles (PubMed:12718872, PubMed:16807356). Upon CCl2 stimulation translocates from the cytoplasm to the membrane and colocalizes with CCR2 at the front of migrating cells (PubMed:15995708).

Diseases

Nephrotic syndrome 17 (NPHS17)

Interacting Proteins

NUP133
SEH1L

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NUP85

References

PMID: 12196509 by Cronshaw J.M., et al. Proteomic analysis of the mammalian nuclear pore complex.

PMID: 15995708 by Terashima Y., et al. Pivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxis.