NUP214 Antibodies

AND NUP214 ELISA kits, NUP214 Proteins

Many biological assays use antibodies to detect NUP214, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NUP214 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NUP214 antibodies...

We validate the specificity of these antibodies to NUP214 by testing them on tissues known to express NUP214 positively and negatively. Browse below to find the NUP214 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NUP214 Infographic by Boster Bio

All NUP214 Products

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Anti-NUP214 Antibody Picoband®

Human, Mouse

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A02408
100 μg/vial

NUP214 Overview

Facts about Nuclear pore complex protein Nup214.

NUP214 3D structure. Source: alphafold

Nuclear pore complex protein Nup214 (NUP214)

May function as a docking site in the receptor-mediated import of substrates across the nuclear pore complex. .

Gene Information

Human
Gene Name:	NUP214
Uniprot:	P35658
Entrez:	8021

Family

Belongs to:

No superfamily

Alternative Names

214 kDa nucleoporin; CAINputative oncogene; D9S46Enuclear pore complex protein Nup214; KIAA0023; MGC104525; N214; nucleoporin 214kD (CAIN); nucleoporin 214kDa; Nucleoporin Nup214; p250; Protein CAN

Molecular Weight

Mass (kDA):
213.62 kDA

Genomic Context


Human

Location:	9q34.13
Sequence:	9; NC_000009.12 (131125586..131234663)

Tissue Specificity

Expressed in thymus, spleen, bone marrow, kidney, brain and testis, but hardly in all other tissues or in whole embryos during development.

Subcellular Localizations

Nucleus, nuclear pore complex. Cytoplasmic side of the nuclear pore complex.

Diseases

Leukemia
Myeloid Leukemia
Acute Lymphocytic Leukemia
Precursor T-cell Lymphoblastic Leukemia-lymphoma
Leukemia, Myelocytic, Acute
Malignant Neoplasms
Neoplasms
Immunologic Deficiency Syndromes
Chromosomal Translocation
Acute Undifferentiated Leukemia
Adult T-cell Lymphoma/leukemia
Hiv Infections

Cell Transformation, Neoplastic
Leukemogenesis
Cytogenetic Abnormality
Neoplasm, Residual
Hematologic Neoplasms
Loss Of Chromosome 9
Hyperplasia

Pathways

Transport
Localization
Nuclear Export
Nuclear Transport
Nuclear Import
Nucleocytoplasmic Transport
Protein Import
Cell Cycle
Mitosis
Pathogenesis
Rna Interference
Interphase
Cell Proliferation

Oncogenesis
Immune Response
Cell Cycle Arrest
Anaphase
G2 Phase
Dna Replication
Cellular Localization

PTMs

Phosphorylation
Cleavage

Glycosylation
Oxidation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NUP214

References

PMID: 1549122 by Von Lindern M., et al. The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA.

PMID: 1630450 by von Lindern M., et al. Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.