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- Table of Contents
Facts about Nuclear pore complex protein Nup153.
Involved in the quality control and retention of unspliced mRNAs from the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species posture constitutive transport element (CTE) at a NXF1- and KHDRBS1-independent method. Mediates TPR anchoring to the nuclear membrane at NPC.
Human | |
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Gene Name: | NUP153 |
Uniprot: | P49790 |
Entrez: | 9972 |
Belongs to: |
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NUP153 family |
CG4453; ; dmNup153; dNup153; HNUP153; N153; nuclear pore complex protein hnup153,153 kDa nucleoporin; nuclear pore complex protein Nup153; nucleoporin 153kD; nucleoporin 153kDa; Nucleoporin Nup153; Nup 153; Nup153 Nucleoporin 153; nup153
Mass (kDA):
153.938 kDA
Human | |
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Location: | 6p22.3 |
Sequence: | 6; NC_000006.12 (17615035..17706925, complement) |
Nucleus. Nucleus membrane. Nucleus, nuclear pore complex. Tightly associated with the nuclear membrane and lamina (By similarity). Localized to the nucleoplasmic side of the nuclear pore complex (NPC) core structure, forming a fibrous structure called the nuclear basket. Dissociates from the NPC structure early during prophase of mitosis. Integrated in the newly assembled nuclear envelope of postmitotic cells early in G1. Colocalized with NUP98 and TPR to the nuclear basket at the nucleoplasmic side of the NPC. Detected in diffuse and discrete intranuclear foci. Remained localized to the nucle
PMID: 8110839 by McMorrow I., et al. Sequence analysis of a cDNA encoding a human nuclear pore complex protein, hnup153.
PMID: 11777942 by Brownawell A.M., et al. Exportin-5, a novel karyopherin, mediates nuclear export of double- stranded RNA binding proteins.