ADP-sugar pyrophosphatase Antibodies

AND NUDT5 ELISA kits, ADP-sugar pyrophosphatase Proteins

Many biological assays use antibodies to detect ADP-sugar pyrophosphatase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADP-sugar pyrophosphatase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADP-sugar pyrophosphatase antibodies...

We validate the specificity of these antibodies to ADP-sugar pyrophosphatase by testing them on tissues known to express NUDT5 positively and negatively. Browse below to find the NUDT5 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NUDT5 Infographic by Boster Bio

All NUDT5 Products

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Product

Figures

Specificity

Applications

Price

NUDT5 (NM_014142) Human Recombinant Protein

$813
Cat # PROTQ9UKK9
20 µg

Anti-NUDT5 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M07530
100 μl/vial

NUDT5 (NM_014142) Human Over-expression Lysate

Human

$628
Cat # LS011164
100 µg

Anti-NUDT5 Antibody Picoband®

Human, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A07530
100 µg/vial

Human NUDT5 ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2269
96 wells/kit, with removable strips.

NUDT5 Overview

Facts about ADP-sugar pyrophosphatase.

NUDT5 3D structure. Source: alphafold

ADP-sugar pyrophosphatase (NUDT5)

Enzyme that can either act as an ADP-sugar pyrophosphatase in lack of diphosphate or catalyze the synthesis of ATP in existence of diphosphate (PubMed:27257257). In lack of diphosphate, hydrolyzes with similar pursuits various modified nucleoside diphosphates like ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP (PubMed:10567213, PubMed:10722730, PubMed:19699693, PubMed:21389046, PubMed:17052728).

Can also hydrolyze additional nucleotide sugars with low activity (PubMed:19699693, PubMed:21389046). In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5- phosphate.

Gene Information

Human
Gene Name:	NUDT5
Uniprot:	Q9UKK9
Entrez:	11164

Family

Belongs to:

Nudix hydrolase family

Alternative Names

EC 3.6.1.-; EC 3.6.1.13; hYSAH1; nucleoside diphosphate linked moiety X-type motif 5; Nucleoside diphosphate-linked moiety X motif 5; nudix (nucleoside diphosphate linked moiety X)-type motif 5; Nudix motif 5; NUDT5; YSA1; YSA1H; YSA1HADP-sugar pyrophosphatase

Molecular Weight

Mass (kDA):
24.328 kDA

Genomic Context


Human

Location:	10p14
Sequence:	10; NC_000010.11 (12165328..12196144, complement)

Tissue Specificity

Widely expressed. Most abundant in liver.

Subcellular Localizations

Nucleus.

Diseases

Growth Retardation
Retinoblastoma
Uterine Cervical Neoplasm
Trematode Infections

Pathways

Dna Replication
Response To Oxidative Stress
Cell Proliferation
Translation
Gene Silencing
Cell Cycle

G1 Phase

PTMs

Cleavage
Ribosylation
Phosphorylation

Acetylation
Oxidation
Dephosphorylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NUDT5

References

PMID: 10567213 by Gasmi L., et al. Cloning, expression and characterization of YSA1H, a human adenosine 5'-diphosphosugar pyrophosphatase possessing a MutT motif.

PMID: 10722730 by Yang H., et al. Cloning and characterization of a new member of the Nudix hydrolases from human and mouse.