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- Table of Contents
Facts about Diphosphoinositol polyphosphate phosphohydrolase 2.
The significant reaction products are ADP and p4a from Ap6A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Human | |
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Gene Name: | NUDT4 |
Uniprot: | Q9NZJ9 |
Entrez: | 11163 |
Belongs to: |
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Nudix hydrolase family |
Diphosphoinositol polyphosphate phosphohydrolase 2
Mass (kDA):
20.306 kDA
Human | |
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Location: | 12q22 |
Sequence: | 12; NC_000012.12 (93377925..93408146) |
Expressed in heart and, at lower level in skeletal muscle, pancreas and kidney.
Cytoplasm.
PMID: 10777568 by Caffrey J.J., et al. Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases. The expanding NUDT family.
PMID: 12121577 by Leslie N.R., et al. Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.